Tenofovir Disoproxil Fumarate + Lamivudine + Efavirenz: Overview
Tenofovir Disoproxil Fumarate + Lamivudine + Efavirenz is a combination medication used in the treatment of HIV (Human Immunodeficiency Virus) infection. It is composed of three active ingredients: Tenofovir Disoproxil Fumarate, Lamivudine, and Efavirenz. This combination medication is manufactured by CIPLA and belongs to the Uncategorised category of medicines. Each pack of this medicine contains 30 tablets in a strip form.
Active Ingredients
– Tenofovir Disoproxil Fumarate
– Lamivudine
– Efavirenz
Pharmacological Properties
Tenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor that works by blocking the activity of an enzyme called reverse transcriptase, which is essential for the HIV virus to replicate. Lamivudine is a nucleoside reverse transcriptase inhibitor that also inhibits the replication of the HIV virus. Efavirenz is a non-nucleoside reverse transcriptase inhibitor that prevents the HIV virus from multiplying in the body.
Indications
This combination medication is indicated for the treatment of HIV-1 infection in adults and pediatric patients weighing at least 40 kg. It is used in combination with other antiretroviral agents as part of a comprehensive HIV treatment regimen.
Contraindications
– Hypersensitivity to any of the active ingredients
– Severe liver impairment
– Severe renal impairment
Dosage
The recommended dosage of Tenofovir Disoproxil Fumarate + Lamivudine + Efavirenz may vary based on the patient’s age, weight, and overall health condition. It is important to follow your healthcare provider’s instructions and the dosage guidelines provided with the medication.
Side Effects
Common side effects of this medication may include:
– Nausea
– Headache
– Dizziness
– Fatigue
– Rash
It is important to report any severe or persistent side effects to your healthcare provider promptly.
Drug Interactions
Tenofovir Disoproxil Fumarate + Lamivudine + Efavirenz may interact with other medications, including:
– Rifampin
– Carbamazepine
– St. John’s Wort
– Certain antacids
Inform your healthcare provider about all the medications you are currently taking to avoid potential drug interactions.
Patient Counseling
– Always take this medication exactly as prescribed by your healthcare provider.
– Do not miss any doses and follow the recommended dosing schedule.
– Inform your healthcare provider about any other medical conditions you have or medications you are taking.
Clinical Evidence
The effectiveness and safety of Tenofovir Disoproxil Fumarate + Lamivudine + Efavirenz have been supported by clinical studies and research conducted in patients with HIV infection. Consult your healthcare provider for more information about the clinical evidence supporting this medication’s use.
Frequently Asked Questions
Q: How should I take Tenofovir Disoproxil Fumarate + Lamivudine + Efavirenz?
A: Take this medication exactly as prescribed by your healthcare provider. Do not change the dosage or dosing schedule without consulting your healthcare provider.
Q: What should I do if I miss a dose of Tenofovir Disoproxil Fumarate + Lamivudine + Efavirenz?
A: If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.
Q: Are there any special precautions or warnings I should be aware of while taking this medication?
A: It is important to inform your healthcare provider about any allergies, medical conditions, or other medications you are taking. Avoid alcohol consumption while taking this medication, as it may increase the risk of side effects.
Q: Can I stop taking Tenofovir Disoproxil Fumarate + Lamivudine + Efavirenz if I start feeling better?
A: No, it is crucial to continue taking this medication as prescribed by your healthcare provider, even if you start feeling better. Stopping the medication prematurely may lead to the development of drug-resistant strains of the HIV virus.
Q: What should I do in case of an overdose of Tenofovir Disoproxil Fumarate + Lamivudine + Efavirenz?
A: In case of an overdose, seek immediate medical attention or contact a poison control center right away. Symptoms of an overdose may include dizziness, nausea, vomiting, and abnormal heart rhythm.
Q: How long does it take for Tenofovir Disoproxil Fumarate + Lamivudine + Efavirenz to show its effects?
A: The onset of action of this medication may vary from person to person. It is essential to continue taking the medication as directed by your healthcare provider for the best results.
By providing detailed information about Tenofovir Disoproxil Fumarate + Lamivudine + Efavirenz, including its active ingredients, pharmacological properties, indications, contraindications, dosage, side effects, drug interactions, patient counseling, and clinical evidence, we aim to enhance your understanding of this medication and its proper use. Always consult your healthcare provider for personalized medical advice and recommendations tailored to your specific healthcare needs.
