Name & Description
The medicine is called Sorafenat 200 MG. It is manufactured by NATCO and falls under the Uncategorised category. It is available in a strip packing type containing 30 tablets. The actual maximum retail price (MRP) of the medicine is Rs. 2350, with a discounted price of Rs. 2327, offering a discount of 0.98%.
Active Ingredients
Sorafenat 200 MG contains the active ingredient sorafenib tosylate, which is a kinase inhibitor that interferes with the growth and spread of cancer cells in the body.
Pharmacological Properties
The pharmacological properties of Sorafenat 200 MG involve its ability to inhibit multiple kinases involved in tumor cell proliferation and angiogenesis. It functions by targeting proteins and pathways that promote cancer growth, leading to the suppression of tumor cell growth and angiogenesis.
Indications
Sorafenat 200 MG is indicated for the treatment of advanced renal cell carcinoma, hepatocellular carcinoma, and radioactive iodine-resistant advanced thyroid carcinoma.
Contraindications
Sorafenat 200 MG is contraindicated in patients with a known hypersensitivity to sorafenib or any other components of the formulation. It should not be used in patients with severe hepatic impairment.
Dosage
The recommended dosage of Sorafenat 200 MG is typically 400 mg (two tablets) taken twice daily, with or without food. The dosage may vary based on the patient’s condition and healthcare provider’s recommendations.
Side Effects
Common side effects of Sorafenat 200 MG may include diarrhea, hand-foot skin reaction, hypertension, fatigue, and rash. Serious side effects such as liver problems, bleeding, and heart problems may also occur and require immediate medical attention.
Drug Interactions
Sorafenat 200 MG may interact with other medications, such as warfarin, rifampin, and phenytoin, potentially affecting their efficacy or increasing the risk of side effects. It is essential to inform your healthcare provider about all the medications you are taking before initiating treatment with Sorafenat.
Patient Counseling
Patient counseling is crucial when prescribing Sorafenat 200 MG. Patients should be informed about the importance of adherence to the prescribed dosage, potential side effects, and the need for regular monitoring during treatment. Additionally, patients should be advised to report any concerning symptoms promptly to their healthcare provider.
Clinical Evidence
Multiple clinical studies have demonstrated the efficacy of Sorafenat 200 MG in the treatment of advanced renal cell carcinoma, hepatocellular carcinoma, and radioactive iodine-resistant advanced thyroid carcinoma. These studies have shown significant improvements in progression-free survival and overall survival rates in patients treated with Sorafenat.
Frequently Asked Questions (FAQs)
Q: What should I do if I miss a dose of Sorafenat 200 MG?
A: If you miss a dose of Sorafenat, take it as soon as you remember unless it is almost time for the next dose. Do not double the dose to compensate for a missed dose. Contact your healthcare provider for further guidance.
Q: Can I take Sorafenat 200 MG with other cancer medications?
A: The use of Sorafenat with other cancer medications should be carefully monitored by your healthcare provider to avoid potential drug interactions. Inform your doctor about all the medications you are taking before starting treatment with Sorafenat.
Q: Are there any dietary restrictions while taking Sorafenat 200 MG?
A: Some patients may be advised to follow specific dietary recommendations while taking Sorafenat, especially regarding grapefruit or grapefruit juice consumption, as it may interact with the medication. Consult your healthcare provider for personalized dietary advice.
Q: Can I drive or operate machinery while taking Sorafenat 200 MG?
A: Sorafenat may cause dizziness or fatigue in some patients. It is advisable to avoid driving or operating heavy machinery if you experience these side effects while taking the medication. Consult your healthcare provider for personalized guidance based on your individual response to the drug.
Q: How long does it take for Sorafenat 200 MG to show results in cancer treatment?
A: The timeframe for observing results with Sorafenat may vary from patient to patient and depends on the type and stage of cancer being treated. Your healthcare provider can provide more specific information about the expected treatment timeline and response assessment.
Q: What should I do in case of severe side effects while taking Sorafenat 200 MG?
A: If you experience severe or intolerable side effects while taking Sorafenat, such as severe liver problems, uncontrolled bleeding, or chest pain, seek immediate medical attention and contact your healthcare provider for further instructions on managing the side effects.
These detailed sections provide comprehensive information about Sorafenat 200 MG, including its active ingredients, pharmacological properties, indications, contraindications, dosage, side effects, drug interactions, patient counseling, clinical evidence, and frequently asked questions to guide patients and healthcare providers in understanding the medication better.
