Sildenafil Citrate 50 mg

Sildenafil Citrate 50 mg is a medication manufactured by Alkem Pharmaceuticals. It falls under the category of medications that are used for the treatment of various conditions, including erectile dysfunction. Each strip contains 4 tablets of Sildenafil Citrate 50 mg. The actual maximum retail price (MRP) of this medication is Rs. 107 per strip, but it is currently available at a discounted price of Rs. 65.5, providing a discount of approximately 38.79%.

Active Ingredients

The active ingredient in Sildenafil Citrate 50 mg is sildenafil citrate. Sildenafil citrate is a phosphodiesterase-5 (PDE5) inhibitor that works by increasing blood flow to the penis during sexual stimulation. This mechanism helps in achieving and maintaining an erection.

Pharmacological Properties

Sildenafil Citrate 50 mg exerts its pharmacological effects by selectively inhibiting the enzyme PDE5, leading to vasodilation and increased blood flow to the penile tissues. This action results in improved erectile function in men with erectile dysfunction. The onset of action of Sildenafil Citrate is typically within 30-60 minutes after ingestion, with effects lasting for up to 4 hours.

Indications

Sildenafil Citrate 50 mg is primarily indicated for the treatment of erectile dysfunction in adult males. It is prescribed to improve sexual function by enabling men to achieve and maintain an erection sufficient for sexual activity. It should be noted that Sildenafil Citrate does not protect against sexually transmitted infections or serve as a form of contraception.

Contraindications

Certain medical conditions and medications may contraindicate the use of Sildenafil Citrate 50 mg. Contraindications include but are not limited to:

– Hypersensitivity to sildenafil or any component of the formulation
– Use of nitrates or nitric oxide donors
– Severe hepatic impairment
– Severe renal impairment
– Unstable angina
– Recent stroke or heart attack
– Severe hypotension

It is important to consult a healthcare provider before initiating treatment with Sildenafil Citrate to assess individual risk factors and contraindications.

Dosage

The recommended dosage of Sildenafil Citrate 50 mg is one tablet taken orally as needed approximately 30-60 minutes before sexual activity. The maximum recommended dosing frequency is once per day. Dose adjustments may be required based on individual response and tolerance to the medication.

Side Effects

Common side effects associated with the use of Sildenafil Citrate 50 mg may include:

– Headache
– Flushing
– Dyspepsia
– Nasal congestion
– Dizziness
– Visual disturbances

Serious side effects such as priapism (prolonged erection), sudden hearing loss, and cardiovascular events have been reported rarely with the use of sildenafil. Patients experiencing severe or persistent side effects should seek immediate medical attention.

Drug Interactions

Sildenafil Citrate 50 mg may interact with certain medications, including:

– Nitrates
– Alpha-blockers
– Protease inhibitors
– Antifungal agents
– Antibiotics

Concomitant use of these medications with Sildenafil Citrate can potentiate the effects and increase the risk of adverse reactions. Patients should inform their healthcare provider about all medications, supplements, and herbal products they are taking before starting Sildenafil Citrate therapy.

Patient Counseling

Patients prescribed Sildenafil Citrate 50 mg should be counseled on the following points:

– Take the medication as directed by the healthcare provider.
– Do not exceed the recommended dose or frequency of administration.
– Sexual stimulation is required for the medication to be effective.
– Avoid consuming alcohol or grapefruit juice while taking Sildenafil Citrate.
– Contact a healthcare provider if erection lasts longer than 4 hours or if experiencing chest pain or dizziness during sexual activity.

Clinical Evidence

Numerous clinical studies have demonstrated the efficacy and safety of Sildenafil Citrate in the treatment of erectile dysfunction. The medication has shown significant improvements in erectile function, satisfaction with sexual intercourse, and overall quality of life in men with varying degrees of erectile dysfunction. Consultation with a healthcare provider is essential for appropriate assessment and management of erectile dysfunction.

Frequently Asked Questions (FAQs)

1. Can Sildenafil Citrate 50 mg be used by women?


Sildenafil Citrate is not indicated for use in women and should only be used as prescribed for men with erectile dysfunction.

2. How quickly does Sildenafil Citrate start working?


Sildenafil Citrate typically starts working within 30-60 minutes after ingestion, with effects lasting up to 4 hours.

3. Is it safe to take Sildenafil Citrate with other medications?


It is important to consult a healthcare provider before taking Sildenafil Citrate with other medications to avoid potential drug interactions.

4. Can Sildenafil Citrate be taken with food?


Sildenafil Citrate can be taken with or without food. However, high-fat meals may delay the onset of action.

5. What should I do if I miss a dose of Sildenafil Citrate?


Sildenafil Citrate is typically taken as needed before sexual activity. If a dose is missed, it can be taken as soon as remembered, with caution not to exceed the maximum recommended dose in a 24-hour period.

By incorporating this expanded information on Sildenafil Citrate 50 mg, patients can gain a comprehensive understanding of the medication’s uses, effects, precautions, and more. Feel free to customize further or reach out for any additional assistance.

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