Introduction to Sacubitril/Valsartan 24/26 MG Tablets
Sacubitril/Valsartan 24/26 MG Tablets is a medication that combines two active ingredients, Sacubitril and Valsartan, in specific dosages to provide therapeutic benefits. This medicine is manufactured by Windlas Biotech Limited and falls under the category of Uncategorised medications. Each strip contains 14 tablets, and the actual MRP of the medicine is Rs. 806. However, customers can avail a significant discount of 81.39%, bringing the discounted price down to just Rs. 150 per strip.
Active Ingredients
Sacubitril/Valsartan Tablets contain a combination of 24 mg of Sacubitril and 26 mg of Valsartan per tablet. These two active ingredients work together to provide a synergistic effect in managing certain medical conditions.
Pharmacological Properties
The pharmacological properties of Sacubitril involve inhibition of neprilysin, an enzyme that degrades natriuretic peptides. Valsartan, on the other hand, is an angiotensin II receptor blocker that prevents the action of a hormone that tightens blood vessels. The combination of these two agents results in increased levels of natriuretic peptides and vasodilation, leading to improved cardiovascular function.
Indications
Sacubitril/Valsartan 24/26 MG Tablets are indicated for the treatment of heart failure with reduced ejection fraction in adult patients. It is usually prescribed when patients are not responding well to standard heart failure medications.
Contraindications
This medication is contraindicated in patients who are allergic to Sacubitril, Valsartan, or any other components of the tablet. It should also be avoided in pregnant women, patients with a history of angioedema related to previous use of ACE inhibitors, and patients with severe liver impairment.
Dosage
The recommended dosage of Sacubitril/Valsartan Tablets is one tablet (24/26 MG) twice daily. It is essential to follow the dosage instructions provided by your healthcare provider to ensure optimal treatment outcomes.
Side Effects
Some common side effects associated with Sacubitril/Valsartan include dizziness, hypotension, cough, elevated potassium levels, and renal impairment. If you experience any severe or persistent side effects, contact your healthcare provider immediately.
Drug Interactions
Caution is advised when combining Sacubitril/Valsartan with other medications that may affect blood pressure, potassium levels, or renal function. Inform your healthcare provider about all the medicines you are taking to prevent potential drug interactions.
Patient Counseling
Patients taking Sacubitril/Valsartan should be counseled on the importance of adherence to the prescribed dosage, monitoring for signs of effects on potassium levels and kidney function, and seeking medical attention if any concerning symptoms arise.
Clinical Evidence
Clinical studies have shown that Sacubitril/Valsartan combination therapy significantly reduces the risk of cardiovascular death and heart failure hospitalization in patients with heart failure and reduced ejection fraction. The evidence supports the use of this medication as an essential component of heart failure management.
Frequently Asked Questions (FAQs)
1. What is Sacubitril/Valsartan used for?
Sacubitril/Valsartan is used for the treatment of heart failure with reduced ejection fraction in adult patients.
2. How should I take Sacubitril/Valsartan Tablets?
Take one tablet of Sacubitril/Valsartan (24/26 MG) twice daily as prescribed by your healthcare provider.
3. Are there any common side effects of Sacubitril/Valsartan?
Common side effects may include dizziness, hypotension, cough, elevated potassium levels, and renal impairment.
4. Can Sacubitril/Valsartan interact with other medications?
It is essential to inform your healthcare provider about all the medications you are taking to prevent potential drug interactions with Sacubitril/Valsartan.
5. What should I do if I miss a dose of Sacubitril/Valsartan?
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
6. Is Sacubitril/Valsartan safe for pregnant women?
Sacubitril/Valsartan is contraindicated in pregnant women. Consult your healthcare provider for alternative treatment options if you are pregnant or planning pregnancy.
7. How long does it take for Sacubitril/Valsartan to show its effects?
The time taken for Sacubitril/Valsartan to show its effects may vary from person to person. It is essential to follow the prescribed dosage and consult your healthcare provider for monitoring.
8. Can I stop taking Sacubitril/Valsartan if I feel better?
Do not stop taking Sacubitril/Valsartan without consulting your healthcare provider, even if you feel better. Abruptly stopping the medication can worsen your condition.
Conclusion
In conclusion, Sacubitril/Valsartan 24/26 MG Tablets offer a promising treatment option for patients with heart failure and reduced ejection fraction. By combining the pharmacological properties of Sacubitril and Valsartan, this medication demonstrates significant clinical benefits in reducing cardiovascular risks. Patients must follow the prescribed dosage, monitor for side effects, and seek medical advice when needed for optimal outcomes. For more information, consult your healthcare provider or pharmacist.
