Rosuvastatin 5 mg + Fenofibrate 160 mg is a combination medication used to treat high cholesterol levels in the blood. This medication is produced by Stafford Laboratories and comes in a strip packing type containing 10 tablets. While the actual MRP of the medication is Rs. 185, it is available at a discounted price of 40, providing a discount of 78.38% to consumers.

Active Ingredients

Rosuvastatin and fenofibrate are the active ingredients in this medication. Rosuvastatin belongs to a class of drugs known as statins, which work by blocking an enzyme in the liver that produces cholesterol. Fenofibrate is a fibrate drug that helps lower triglycerides and increase HDL (good) cholesterol levels in the blood.

Pharmacological Properties

The combination of rosuvastatin and fenofibrate works synergistically to reduce cholesterol levels in the blood. Rosuvastatin inhibits the production of cholesterol in the liver, while fenofibrate helps lower triglyceride levels. This dual mechanism of action makes the medication effective in managing lipid profiles.


Rosuvastatin 5 mg + Fenofibrate 160 mg is indicated for the treatment of high levels of cholesterol and triglycerides in the blood. It is prescribed to patients with hyperlipidemia to reduce their risk of cardiovascular events such as heart attacks and strokes.


This medication is contraindicated in individuals with a known allergy to rosuvastatin, fenofibrate, or any other component of the formulation. It should not be used in patients with active liver disease or unexplained persistent elevations of liver function tests.


The typical dosage of Rosuvastatin 5 mg + Fenofibrate 160 mg is one tablet taken orally once daily, preferably with food. The dose may vary depending on the individual patient’s lipid profile and medical history. It is important to follow the prescribed dosage regimen provided by your healthcare provider.

Side Effects

Common side effects of this medication include muscle pain, weakness, abdominal pain, nausea, and diarrhea. In rare cases, it may cause liver problems or an allergic reaction. If you experience any severe or persistent side effects, contact your healthcare provider immediately.

Drug Interactions

Rosuvastatin and fenofibrate can interact with other medications, including certain antibiotics, antifungal drugs, and cholesterol-lowering agents. It is important to inform your doctor about all the medications you are currently taking to avoid potential drug interactions that could reduce the effectiveness or increase the risk of side effects of this combination therapy.

Patient Counseling

Patient counseling is essential for ensuring the safe and effective use of Rosuvastatin 5 mg + Fenofibrate 160 mg. Patients should be advised to take the medication as prescribed, follow a healthy diet low in saturated fats and cholesterol, engage in regular physical activity, and attend regular follow-up appointments with their healthcare provider for monitoring of lipid levels and overall health.

Clinical Evidence

The efficacy and safety of rosuvastatin and fenofibrate in combination therapy have been supported by clinical studies demonstrating their ability to reduce cholesterol and triglyceride levels in patients with hyperlipidemia. These studies have shown a reduction in the risk of cardiovascular events in patients treated with this combination medication.

Frequently Asked Questions

1. Can I take Rosuvastatin 5 mg + Fenofibrate 160 mg without food?

It is recommended to take this medication with food to improve its absorption and reduce the risk of stomach upset.

2. How long does it take to see the effects of this medication on cholesterol levels?

The effects of rosuvastatin and fenofibrate on cholesterol levels can be observed within a few weeks of starting the treatment. However, it may take several months to achieve optimal results.

3. What should I do if I miss a dose of Rosuvastatin 5 mg + Fenofibrate 160 mg?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

4. Are there any lifestyle changes I need to make while taking this medication?

It is important to adopt a healthy lifestyle while taking Rosuvastatin 5 mg + Fenofibrate 160 mg. This includes following a heart-healthy diet, engaging in regular exercise, avoiding smoking, and limiting alcohol consumption.

5. Can I drink grapefruit juice while taking this medication?

Grapefruit juice can interact with certain statin medications, including rosuvastatin, and increase the risk of side effects. It is advisable to avoid consuming grapefruit juice while on this combination therapy.

6. How often should I have my lipid levels checked while taking Rosuvastatin 5 mg + Fenofibrate 160 mg?

Your healthcare provider will determine the frequency of lipid level monitoring based on your individual profile and response to the medication. Typically, lipid levels are checked regularly, especially during the initial phase of treatment.

Overall, Rosuvastatin 5 mg + Fenofibrate 160 mg is a valuable combination medication for the management of high cholesterol and triglyceride levels. By following the prescribed regimen, adopting a healthy lifestyle, and staying informed about potential side effects and drug interactions, patients can effectively control their lipid profiles and reduce their risk of cardiovascular complications.

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