Description: Rosuvastatin 10 mg + Fenofibrate 145 mg is a combination medication used to treat high cholesterol and triglyceride levels. It contains two active ingredients, rosuvastatin and fenofibrate, which work together to help lower lipid levels in the blood.

Active Ingredients:

Rosuvastatin: Rosuvastatin is a statin drug that works by decreasing the production of cholesterol in the liver. It specifically inhibits the enzyme HMG-CoA reductase, which plays a key role in cholesterol synthesis.

Fenofibrate: Fenofibrate belongs to a group of medications known as fibric acid derivatives. It works by reducing the production of triglycerides in the liver and increasing the elimination of triglycerides from the body.

Pharmacological Properties:

The combination of rosuvastatin and fenofibrate provides complementary mechanisms of action in lowering cholesterol and triglycerides. Rosuvastatin primarily acts on LDL cholesterol (“bad” cholesterol) levels, while fenofibrate targets triglycerides and raises HDL cholesterol (“good” cholesterol) levels.


Rosuvastatin 10 mg + Fenofibrate 145 mg is indicated for the treatment of mixed dyslipidemia, a condition characterized by elevated levels of cholesterol and triglycerides in the blood. It is prescribed to patients with high cardiovascular risk to reduce the occurrence of cardiovascular events.


This medication is contraindicated in individuals with a known hypersensitivity to rosuvastatin, fenofibrate, or any of the excipients in the formulation. It should not be used in patients with active liver disease or unexplained persistent elevations in liver function tests.


The usual recommended dose of Rosuvastatin 10 mg + Fenofibrate 145 mg is one tablet taken orally once daily, preferably with food. It is important to follow the dosage instructions provided by your healthcare provider to ensure the optimal therapeutic effect.

Side Effects:

Common side effects associated with this medication may include muscle pain, headache, abdominal discomfort, and abnormal liver function tests. If you experience any severe or persistent side effects, consult your healthcare provider immediately.

Drug Interactions:

Before taking Rosuvastatin 10 mg + Fenofibrate 145 mg, inform your healthcare provider about all the medications you are currently taking, including prescription, over-the-counter, and herbal supplements. Some medications may interact with this combination, potentially affecting its efficacy or increasing the risk of side effects.

Patient Counseling:

It is important to adhere to a healthy lifestyle, including a balanced diet, regular exercise, and weight management, while taking Rosuvastatin 10 mg + Fenofibrate 145 mg. Follow-up with your healthcare provider regularly to monitor your lipid levels and overall health.

Clinical Evidence:

Several clinical studies have demonstrated the efficacy and safety of the combination of rosuvastatin and fenofibrate in lowering cholesterol and triglyceride levels. Consult your healthcare provider for more information on the clinical evidence supporting the use of this medication.

Frequently Asked Questions:

Q: Can I take Rosuvastatin 10 mg + Fenofibrate 145 mg with other cholesterol-lowering medications?

A: It is important to consult your healthcare provider before combining this medication with other cholesterol-lowering drugs to prevent potential drug interactions and adverse effects.

Q: How long does it take to see the effects of Rosuvastatin 10 mg + Fenofibrate 145 mg?

A: The onset of action may vary among individuals, but significant improvements in lipid levels can usually be observed within a few weeks of starting the medication.

Q: Are there any dietary restrictions while taking Rosuvastatin 10 mg + Fenofibrate 145 mg?

A: While there are no specific dietary restrictions, it is advisable to follow a healthy diet low in saturated fats and cholesterol to enhance the efficacy of the medication.

Q: What should I do if I miss a dose of Rosuvastatin 10 mg + Fenofibrate 145 mg?

A: If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

Q: Can Rosuvastatin 10 mg + Fenofibrate 145 mg cause muscle pain?

A: Muscle pain, known as myopathy, is a potential side effect of this medication. If you experience unexplained muscle pain, weakness, or tenderness, contact your healthcare provider promptly.

For more information on Rosuvastatin 10 mg + Fenofibrate 145 mg, consult your healthcare provider or pharmacist.

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