RIVAROXABAN 10 MG: A Comprehensive Guide

RIVAROXABAN 10 MG is a medication that belongs to the anticoagulant class of drugs. It is manufactured by MASCOT HEALTH SERIES and comes in a strip packaging containing 14 tablets. The actual MRP of this medicine is Rs. 252, but it is available at a discounted price of Rs. 111, offering a discount of 55.95%.

Active Ingredients

The active ingredient in RIVAROXABAN 10 MG is rivaroxaban, which is a direct factor Xa inhibitor. It works by inhibiting the activity of factor Xa in the coagulation cascade, thereby preventing the formation of blood clots.

Pharmacological Properties

Rivaroxaban exerts its anticoagulant effects by selectively inhibiting factor Xa, which is a key enzyme in the coagulation cascade. By blocking factor Xa, rivaroxaban prevents the conversion of prothrombin to thrombin, thereby inhibiting the formation of fibrin clots. This mechanism of action makes rivaroxaban an effective anticoagulant for the prevention and treatment of various thromboembolic disorders.

Indications

RIVAROXABAN 10 MG is indicated for the following conditions:

  • Prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation
  • Treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE)
  • Prophylaxis of venous thromboembolism (VTE) in patients undergoing hip or knee replacement surgery

Contraindications

RIVAROXABAN 10 MG is contraindicated in patients with a history of hypersensitivity to rivaroxaban or any other components of the formulation. It should also be avoided in patients with active major bleeding or severe hepatic impairment.

Dosage

The recommended dosage of RIVAROXABAN 10 MG for different indications is as follows:

  • Non-valvular atrial fibrillation: 20 mg once daily with the evening meal
  • DVT and PE treatment: 15 mg twice daily for the first 21 days, followed by 20 mg once daily
  • VTE prophylaxis in hip/knee replacement surgery: 10 mg once daily for 35 days

Side Effects

Common side effects of RIVAROXABAN 10 MG may include:

  • Bleeding
  • Bruising
  • Headache
  • Dizziness

Contact your healthcare provider if you experience any severe or persistent side effects while taking this medication.

Drug Interactions

RIVAROXABAN 10 MG may interact with certain medications and substances, including:

  • Anticoagulants
  • Antiplatelet drugs
  • Nonsteroidal anti-inflammatory drugs (NSAIDs)

It is important to inform your healthcare provider about all the medications you are currently taking to avoid potential drug interactions.

Patient Counseling

Before taking RIVAROXABAN 10 MG, patients should be counseled on the following points:

  • Take the medication exactly as prescribed by your healthcare provider
  • Do not stop taking the medication abruptly without consulting your doctor
  • Report any unusual bleeding or bruising to your healthcare provider

Clinical Evidence

Several clinical studies have demonstrated the efficacy and safety of RIVAROXABAN 10 MG in the management of thromboembolic disorders. These studies have shown that rivaroxaban is non-inferior to traditional anticoagulants and may offer certain advantages, such as fixed dosing without the need for routine monitoring.

Frequently Asked Questions

Q: Can I take RIVAROXABAN 10 MG with other blood thinners?

A: It is generally not recommended to take RIVAROXABAN 10 MG with other blood thinners without consulting your healthcare provider due to an increased risk of bleeding.

Q: What should I do if I miss a dose of RIVAROXABAN 10 MG?

A: If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. Do not double dose to make up for a missed dose.

Q: How long should I take RIVAROXABAN 10 MG for deep vein thrombosis (DVT) treatment?

A: The duration of treatment for DVT with RIVAROXABAN 10 MG is determined by your healthcare provider based on your individual condition. Follow your doctor’s recommendations carefully.

Q: Are there any dietary restrictions while taking RIVAROXABAN 10 MG?

A: There are no specific dietary restrictions associated with RIVAROXABAN 10 MG. However, it is important to maintain a balanced diet while taking this medication.

Q: What should I do in case of an overdose of RIVAROXABAN 10 MG?

A: In case of an overdose, seek immediate medical attention or contact a poison control center. Symptoms of overdose may include increased bleeding risk.

This comprehensive guide provides detailed information about RIVAROXABAN 10 MG, including its active ingredients, pharmacological properties, indications, contraindications, dosage, side effects, drug interactions, patient counseling, clinical evidence, and frequently asked questions. If you have any further inquiries or concerns, consult with your healthcare provider for personalized guidance.

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