PRAMIPEXOLE DIHYDROCHLORIDE 1 MG
PRAMIPEXOLE DIHYDROCHLORIDE 1 MG is a medication produced by UNITED BIOCEUTICALS and falls under the category of Uncategorised medicines. It is available in a strip packaging containing 10 tablets. The actual market price of PRAMIPEXOLE DIHYDROCHLORIDE 1 MG is Rs. 146, but it is currently being offered at a discounted price of 90, representing a discount of 38.36%.
Active Ingredients
The active ingredient in PRAMIPEXOLE DIHYDROCHLORIDE 1 MG is pramipexole dihydrochloride, which is a dopamine agonist that works by stimulating dopamine receptors in the brain.
Pharmacological Properties
PRAMIPEXOLE DIHYDROCHLORIDE 1 MG has potent agonist activity at dopamine D2 and D3 receptors. It also has moderate affinity for the dopamine D4, serotonin 5-HT1A and 5-HT2A, and α2-adrenergic receptors. These pharmacological properties make it effective in treating symptoms of Parkinson’s disease and restless legs syndrome.
Indications
PRAMIPEXOLE DIHYDROCHLORIDE 1 MG is commonly prescribed for the treatment of Parkinson’s disease, a progressive nervous system disorder that affects movement. It is also used to alleviate symptoms of restless legs syndrome, a condition characterized by uncomfortable sensations in the legs and an irresistible urge to move them.
Contraindications
PRAMIPEXOLE DIHYDROCHLORIDE 1 MG should not be used in patients with a known hypersensitivity to pramipexole or any other components of the formulation. It is contraindicated in individuals with severe renal impairment and in those with a history of impulsive or pathological gambling.
Dosage
The usual starting dose of PRAMIPEXOLE DIHYDROCHLORIDE 1 MG for Parkinson’s disease is 0.125 mg three times daily. The dose can be gradually increased every 5-7 days based on the individual’s response and tolerability. The recommended dose for restless legs syndrome is 0.125 mg once daily, 2-3 hours before bedtime.
Side Effects
Common side effects of PRAMIPEXOLE DIHYDROCHLORIDE 1 MG include nausea, dizziness, headache, fatigue, and insomnia. Less frequently reported side effects include hallucinations, orthostatic hypotension, and impulse control disorders. It is important to inform healthcare providers about any unusual or severe side effects experienced while taking this medication.
Drug Interactions
PRAMIPEXOLE DIHYDROCHLORIDE 1 MG may interact with medications that affect dopamine levels in the brain, such as antipsychotics, metoclopramide, and certain antidepressants. It is important to inform healthcare providers about all prescription, over-the-counter, and herbal products being taken to avoid potential drug interactions.
Patient Counseling
Patient counseling is essential for individuals taking PRAMIPEXOLE DIHYDROCHLORIDE 1 MG. Patients should be advised to take the medication exactly as prescribed and to report any new or worsening symptoms to their healthcare provider. It is important to avoid sudden discontinuation of the medication without medical guidance due to the risk of withdrawal symptoms.
Clinical Evidence
Clinical studies have demonstrated the efficacy of PRAMIPEXOLE DIHYDROCHLORIDE 1 MG in improving motor symptoms in patients with Parkinson’s disease. Additionally, research has shown that it can provide significant relief from symptoms of restless legs syndrome, improving sleep quality and overall quality of life for affected individuals.
Frequently Asked Questions
1. How long does it take for PRAMIPEXOLE DIHYDROCHLORIDE 1 MG to start working?
The onset of action of PRAMIPEXOLE DIHYDROCHLORIDE 1 MG varies from individual to individual. Some patients may experience improvement in symptoms within a few days to a few weeks of starting the medication.
2. Can PRAMIPEXOLE DIHYDROCHLORIDE 1 MG be taken with food?
PRAMIPEXOLE DIHYDROCHLORIDE 1 MG can be taken with or without food. However, it is recommended to take it consistently, either always with food or always on an empty stomach, to maintain consistent drug levels in the body.
3. What should I do if I miss a dose of PRAMIPEXOLE DIHYDROCHLORIDE 1 MG?
If a dose of PRAMIPEXOLE DIHYDROCHLORIDE 1 MG is missed, it should be taken as soon as remembered. However, if it is almost time for the next dose, the missed dose should be skipped, and the regular dosing schedule should be resumed. Double doses should not be taken to make up for a missed dose.
4. Is it safe to drive or operate machinery while taking PRAMIPEXOLE DIHYDROCHLORIDE 1 MG?
PRAMIPEXOLE DIHYDROCHLORIDE 1 MG may cause dizziness, drowsiness, or vision changes, which can impair the ability to drive or operate machinery. Patients should exercise caution while engaging in activities that require mental alertness until they know how the medication affects them.
5. Can PRAMIPEXOLE DIHYDROCHLORIDE 1 MG be used during pregnancy or breastfeeding?
PRAMIPEXOLE DIHYDROCHLORIDE 1 MG should only be used during pregnancy or breastfeeding if the potential benefits outweigh the risks. Women who are pregnant or breastfeeding should consult with their healthcare provider before starting this medication.
Summary
In conclusion, PRAMIPEXOLE DIHYDROCHLORIDE 1 MG is a medication containing pramipexole dihydrochloride that is commonly prescribed for Parkinson’s disease and restless legs syndrome. It acts as a dopamine agonist and has a favorable efficacy profile supported by clinical evidence. Prior to starting this medication, patients should be aware of its active ingredients, pharmacological properties, indications, contraindications, dosage recommendations, potential side effects, drug interactions, and patient counseling points. Regular communication with healthcare providers and adherence to prescribed regimens are essential for optimal therapeutic outcomes.
