### PIOGLITAZONE 30 MG

Pioglitazone 30 mg is a medication manufactured by BIOCHEM, falling into the uncategorized category of medicines. It is available in a strip packing type containing 10 tablets. The actual MRP of this medicine is Rs. 114.8, but it is being offered at a discounted price of 28 with a discount of 75.61%.

#### Active Ingredients
The active ingredient in Pioglitazone 30 mg is pioglitazone hydrochloride.

#### Pharmacological Properties
Pioglitazone is a thiazolidinedione antidiabetic agent that works by decreasing insulin resistance in the body. It primarily acts by increasing the sensitivity of peripheral tissues to insulin, thereby improving glucose uptake and reducing blood sugar levels.

#### Indications
Pioglitazone 30 mg is commonly prescribed for the treatment of type 2 diabetes mellitus in adults. It is used in conjunction with diet and exercise to control blood sugar levels in patients who cannot manage their condition through lifestyle modifications alone.

#### Contraindications
– Patients with a known allergy or hypersensitivity to pioglitazone or any other components of the medication should not use Pioglitazone 30 mg.
– It is contraindicated in patients with heart failure, liver disease, or bladder cancer.

#### Dosage
The typical recommended dose of Pioglitazone 30 mg is one tablet taken orally once a day, with or without food. The dosage may vary based on individual patient requirements and the direction of the prescribing healthcare provider.

#### Side Effects
Some common side effects of Pioglitazone 30 mg may include:
– Weight gain
– Edema (fluid retention)
– Headache
– Muscle pain
– Hypoglycemia (low blood sugar) when combined with other antidiabetic medications

#### Drug Interactions
Pioglitazone may interact with certain medications, such as:
– Insulin or other antidiabetic drugs
– Gemfibrozil
– Rifampin
It is essential to inform your healthcare provider about all the medications you are taking to prevent potential drug interactions.

#### Patient Counseling
– Patients should follow a well-balanced diet and exercise regimen while taking Pioglitazone 30 mg as part of their diabetes management plan.
– Regular monitoring of blood sugar levels and periodic check-ups are important to evaluate the effectiveness and safety of the medication.

#### Clinical Evidence
Clinical studies have shown that Pioglitazone 30 mg, when used as part of a comprehensive treatment plan, can effectively improve glycemic control in patients with type 2 diabetes. It has demonstrated significant reductions in HbA1c levels and has been associated with a decreased risk of cardiovascular events in certain populations.

#### Frequently Asked Questions

What should I do if I miss a dose of Pioglitazone 30 mg?

If you miss a dose of Pioglitazone, take it as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

Can Pioglitazone cause hypoglycemia (low blood sugar)?

Pioglitazone itself is not known to cause hypoglycemia when used as a monotherapy. However, if you are taking Pioglitazone along with other antidiabetic medications that can lower blood sugar levels, there is a risk of hypoglycemia. It’s essential to monitor your blood sugar levels closely and consult with your healthcare provider if you experience symptoms of low blood sugar.

How long does it take for Pioglitazone to start working?

Pioglitazone may start to show its effects in improving blood sugar control within a few weeks of starting the medication. However, it may take up to 2-3 months to experience the full benefits of Pioglitazone therapy. It’s important to continue taking the medication as prescribed by your doctor, even if you do not see immediate results.

Is Pioglitazone safe for use in elderly patients?

Pioglitazone can be used in elderly patients with type 2 diabetes; however, caution should be exercised due to the increased risk of adverse effects, such as fluid retention, heart failure, and fractures in this population. The dosage may need to be adjusted based on individual health conditions and renal function.

Can Pioglitazone be used during pregnancy?

Pioglitazone is not recommended for use during pregnancy, as it may cause harm to the unborn baby. If you are pregnant or planning to become pregnant, consult with your healthcare provider for alternative treatment options to manage your diabetes effectively and safely.

How does Pioglitazone differ from other antidiabetic medications?

Pioglitazone belongs to the class of thiazolidinediones, which work by targeting insulin resistance in the body. Unlike some other antidiabetic drugs that stimulate insulin secretion or inhibit glucose production in the liver, Pioglitazone primarily improves insulin sensitivity in peripheral tissues, making it a valuable treatment option in certain patient populations.

By providing comprehensive information on Pioglitazone 30 mg, including its active ingredients, pharmacological properties, indications, contraindications, dosage, side effects, drug interactions, patient counseling, and clinical evidence, patients can make informed decisions about its use in managing their diabetes effectively.

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