Introduction to Palbociclib 125 mg
Palbociclib 125 mg is a medication produced by Natco Pharmaceuticals. It falls under the category of uncategorised medicines and is packaged in a bottle containing 21 capsules. The actual maximum retail price (MRP) of Palbociclib 125 mg is Rs. 4500, but it is currently being offered at a discounted price of Rs. 3100, reflecting a discount of 31.11%.
Active Ingredients of Palbociclib 125 mg
The active ingredient in Palbociclib 125 mg is palbociclib itself. Palbociclib is a targeted therapy medication commonly used in the treatment of certain types of breast cancer.
Pharmacological Properties of Palbociclib
Palbociclib acts as a selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6), which are enzymes involved in cell cycle progression. By inhibiting these enzymes, Palbociclib helps to slow down the growth and division of cancer cells in the body.
Indications for Palbociclib 125 mg
Palbociclib 125 mg is primarily indicated for the treatment of hormone receptor-positive, HER2-negative advanced or metastatic breast cancer in combination with an aromatase inhibitor or fulvestrant.
Contraindications of Palbociclib 125 mg
Palbociclib 125 mg is contraindicated in patients who have hypersensitivity to the active ingredient palbociclib or any of the other components of the medication. It should not be used in pregnant women as it may cause harm to the developing fetus.
Dosage of Palbociclib 125 mg
The recommended dose of Palbociclib 125 mg is 125 mg taken orally once daily with or without food for 21 consecutive days, followed by 7 days off treatment to comprise a complete cycle of 28 days.
Side Effects of Palbociclib 125 mg
Common side effects associated with Palbociclib 125 mg include neutropenia (low white blood cell count), leukopenia (low white blood cell count), fatigue, nausea, hair thinning, diarrhea, and infections. It is essential to discuss any side effects with your healthcare provider.
Drug Interactions with Palbociclib 125 mg
Palbociclib may interact with certain medications, such as strong inhibitors or inducers of CYP3A or P-glycoprotein. It is important to inform your healthcare provider about all the medications you are currently taking to avoid potential drug interactions.
Patient Counseling for Palbociclib 125 mg
Patients taking Palbociclib 125 mg should be advised to adhere to the prescribed dosing schedule and follow all instructions provided by their healthcare provider. They should also be informed about the potential side effects of the medication and when to seek medical attention.
Clinical Evidence on Palbociclib 125 mg
Clinical studies have demonstrated the efficacy of Palbociclib 125 mg in combination with hormonal therapies for the treatment of hormone receptor-positive advanced breast cancer. These studies have shown improvements in progression-free survival and overall survival rates in patients receiving Palbociclib.
Frequently Asked Questions (FAQs) about Palbociclib 125 mg
Q: Can Palbociclib 125 mg be used as a standalone treatment for breast cancer?
A: Palbociclib 125 mg is typically used in combination with other hormonal therapies for the treatment of advanced breast cancer. It is not usually recommended as a standalone treatment.
Q: How should Palbociclib 125 mg be stored?
A: Palbociclib 125 mg should be stored at room temperature away from moisture and heat. Keep the medication out of reach of children.
Q: Is Palbociclib 125 mg suitable for all patients with breast cancer?
A: Palbociclib 125 mg is specifically indicated for hormone receptor-positive, HER2-negative advanced or metastatic breast cancer. It may not be suitable for all patients with breast cancer, so it is essential to consult with a healthcare provider.
Q: What should I do if I miss a dose of Palbociclib 125 mg?
A: If you miss a dose of Palbociclib 125 mg, take it as soon as you remember on the same day. If it is already the next day, do not take the missed dose and resume your regular dosing schedule.
Q: Are there any dietary restrictions while taking Palbociclib 125 mg?
A: There are no specific dietary restrictions associated with Palbociclib 125 mg. However, it is important to maintain a healthy and balanced diet to support overall health and well-being during cancer treatment.
Q: How long should I continue taking Palbociclib 125 mg?
A: The duration of treatment with Palbociclib 125 mg should be determined by your healthcare provider based on your individual response to the medication and treatment goals. Do not discontinue the medication without consulting your healthcare provider.
