OXYMETAZOLINE HYDROCHLORIDE 0.05%w/v (DROP) – Detailed Information

OXYMETAZOLINE HYDROCHLORIDE 0.05%w/v (Drop) is a medication commonly used for nasal congestion relief. It belongs to the category of nasal decongestants and is manufactured by CIPLA. Each pack contains 10ml of the solution. The actual MRP of this medication is Rs. 64.13, but it is available at a discounted price of Rs. 54, offering a 15.8% discount.

Active Ingredients

The active ingredient in OXYMETAZOLINE HYDROCHLORIDE 0.05%w/v (Drop) is Oxymetazoline Hydrochloride. It is a vasoconstrictor that works by narrowing blood vessels in the nasal passages. This action reduces swelling and congestion in the nasal tissues, making it easier to breathe.

Pharmacological Properties

Oxymetazoline, the main component of this medication, acts on alpha-adrenergic receptors in the nasal mucosa. By stimulating these receptors, it constricts the blood vessels in the nasal lining, leading to a decrease in nasal congestion and swelling. This pharmacological action helps in clearing nasal passages and improving airflow.


OXYMETAZOLINE HYDROCHLORIDE 0.05%w/v (Drop) is indicated for the temporary relief of nasal congestion caused by conditions such as the common cold, sinusitis, and allergies. It can help alleviate symptoms like stuffy or runny nose, sneezing, and sinus pressure.


This medication is contraindicated in individuals with a known hypersensitivity to oxymetazoline or any other components of the formulation. It should not be used in patients with narrow-angle glaucoma or certain medical conditions without medical supervision.


The recommended dosage for OXYMETAZOLINE HYDROCHLORIDE 0.05%w/v (Drop) is usually one to two drops in each nostril every 10 to 12 hours, or as directed by a healthcare provider. It is essential to follow the dosing instructions provided on the packaging or prescribed by a healthcare professional.

Side Effects

Common side effects of OXYMETAZOLINE HYDROCHLORIDE 0.05%w/v (Drop) may include temporary burning, stinging, sneezing, or increased nasal discharge. These effects are usually mild and transient. However, severe side effects such as irregular heartbeat or severe dizziness should be reported to a healthcare provider immediately.

Drug Interactions

It is important to inform your healthcare provider about all the medications, supplements, or herbal products you are taking before using OXYMETAZOLINE HYDROCHLORIDE 0.05%w/v (Drop). Certain drugs, such as monoamine oxidase inhibitors (MAOIs) or other nasal decongestants, may interact with oxymetazoline and lead to adverse effects.

Patient Counseling

Patients using OXYMETAZOLINE HYDROCHLORIDE 0.05%w/v (Drop) should be advised to administer the drops as directed and avoid exceeding the recommended dosage. It is essential to avoid prolonged use of this medication to prevent rebound congestion. If symptoms persist or worsen, patients should seek medical advice.

Clinical Evidence

Clinical studies have demonstrated the effectiveness of oxymetazoline in providing relief from nasal congestion associated with various conditions. The vasoconstrictive properties of the drug have shown to improve nasal airflow and reduce congestion in patients suffering from colds or allergies.

Frequently Asked Questions (FAQs)


A: OXYMETAZOLINE HYDROCHLORIDE typically begins to work within a few minutes after administration, with the maximum effect usually achieved within 15 to 30 minutes.


A: It is important to consult a healthcare provider before using OXYMETAZOLINE HYDROCHLORIDE in children, as the dosage and safety considerations may vary for pediatric patients.

Q: What should I do if I miss a dose of OXYMETAZOLINE HYDROCHLORIDE?

A: If you miss a dose of OXYMETAZOLINE HYDROCHLORIDE, you can administer it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double dose to compensate for a missed dose.

Q: Are there any lifestyle modifications recommended while using OXYMETAZOLINE HYDROCHLORIDE?

A: It is advisable to avoid excessive caffeine consumption and maintain adequate hydration while using OXYMETAZOLINE HYDROCHLORIDE to support the effectiveness of the medication in relieving nasal congestion.

Overall, OXYMETAZOLINE HYDROCHLORIDE 0.05%w/v (Drop) is a trusted nasal decongestant effective in providing temporary relief from nasal congestion due to various respiratory conditions. It is important to use this medication as directed and seek medical advice if needed.

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