Ketoconazole shampoo 1% is a medication used to treat fungal infections of the skin like dandruff, seborrheic dermatitis, and tinea versicolor. It is a medicated shampoo that contains the active ingredient ketoconazole, which has antifungal properties.

Active Ingredients:

The active ingredient in Ketoconazole Shampoo 1% is ketoconazole, which belongs to a class of medications called antifungals. It works by stopping the growth of fungi that cause infections on the skin.

Pharmacological Properties:

Ketoconazole acts by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes. This disrupts the normal function of the fungi, leading to their death. It is effective against a wide range of fungi, including those causing dandruff and other skin infections.


Ketoconazole shampoo 1% is indicated for the treatment of fungal infections of the skin, such as dandruff, seborrheic dermatitis, and tinea versicolor. It helps relieve symptoms like itching, flaking, and redness associated with these conditions.


Ketoconazole shampoo 1% should not be used by individuals who are allergic to ketoconazole or any other ingredients in the shampoo. It should also be avoided in patients with a known hypersensitivity to imidazole antifungals.


For the treatment of dandruff and seborrheic dermatitis, apply Ketoconazole Shampoo 1% to wet hair, lather, and leave on the scalp for 5 minutes before rinsing thoroughly. Use twice a week for 2-4 weeks or as directed by your healthcare provider.

Side Effects:

Common side effects of ketoconazole shampoo may include scalp irritation, dryness, or oiliness. In some cases, it may cause allergic reactions like rash or hives. If you experience severe side effects or worsening of symptoms, discontinue use and consult a doctor.

Drug Interactions:

Ketoconazole shampoo 1% can interact with certain medications like oral anticoagulants, cyclosporine, and some statins. Inform your healthcare provider about all the medications you are taking to avoid potential drug interactions.

Patient Counseling:

Patients using Ketoconazole Shampoo 1% should follow the instructions provided by their healthcare provider or pharmacist for proper application. It is important to avoid contact with eyes and mucous membranes. In case of accidental ingestion, seek medical help immediately.

Clinical Evidence:

Numerous clinical studies have demonstrated the efficacy of ketoconazole shampoo in the treatment of fungal skin infections, particularly dandruff and seborrheic dermatitis. The antifungal properties of ketoconazole have shown significant improvement in symptoms and reduction in fungal growth on the scalp.

Frequently Asked Questions:

1. How often should I use Ketoconazole Shampoo 1%?

The recommended frequency of use is twice a week for 2-4 weeks or as directed by your healthcare provider.

2. Can Ketoconazole Shampoo be used on color-treated hair?

Yes, Ketoconazole Shampoo can be used on color-treated hair, but it is advisable to consult your hairstylist or dermatologist for personalized recommendations.

3. Is Ketoconazole Shampoo safe for pregnant women?

Pregnant women should consult their healthcare provider before using Ketoconazole Shampoo to weigh the potential benefits against any risks to the fetus.

4. What should I do if I accidentally swallow Ketoconazole Shampoo?

In case of accidental ingestion, seek immediate medical assistance or contact a poison control center.

5. Can Ketoconazole Shampoo cause hair loss?

Hair loss is not a common side effect of Ketoconazole Shampoo. If you experience unusual hair loss, discontinue use and consult a healthcare professional.

In conclusion, Ketoconazole Shampoo 1% is a trusted medication for the treatment of fungal skin infections such as dandruff and seborrheic dermatitis. With proper usage and precautions, it can effectively alleviate symptoms and improve the overall health of your scalp. If you have any concerns or further inquiries, consult your healthcare provider for personalized advice.

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