KETOCONAZOLE + NEOMYCIN SULPHATE + IODOCHLORHYDROXYQUINOLINE + TOLNAFTATE + CLOBETASOL PROPIONATE

Ketoconazole + Neomycin Sulphate + Iodochlorhydroxyquinoline + Tolnaftate + Clobetasol Propionate is a topical medication that combines multiple active ingredients to treat various skin conditions. This medication is formulated as a cream containing Ketoconazole 2.00% w/w, Neomycin Sulphate 0.10% w/w, Iodochlorhydroxyquinoline 1.00% w/w, Tolnaftate 1.00% w/w, and Clobetasol Propionate 0.05% w/w.

Active Ingredients:

– Ketoconazole: An antifungal agent used to treat fungal infections of the skin.
– Neomycin Sulphate: An antibiotic that helps treat bacterial infections.
– Iodochlorhydroxyquinoline: An antifungal and antibacterial agent.
– Tolnaftate: An antifungal medication that treats fungal skin infections.
– Clobetasol Propionate: A potent steroid used to reduce inflammation and itching in various skin conditions.

Pharmacological Properties:

The combination of active ingredients in this medication provides broad-spectrum antimicrobial and anti-inflammatory properties. Ketoconazole and Tolnaftate work to target and eliminate fungal infections, while Neomycin Sulphate and Iodochlorhydroxyquinoline fight against bacterial infections. Clobetasol Propionate helps reduce inflammation, redness, and itching associated with skin conditions.

Indications:

This medication is indicated for the treatment of various skin conditions, including fungal and bacterial infections, eczema, dermatitis, and inflammation associated with these conditions.

Contraindications:

– Hypersensitivity to any of the active ingredients
– Viral skin infections such as herpes or chickenpox
– Untreated skin infections
– Broken or injured skin
– Pregnancy and lactation (unless advised by a healthcare provider)

Dosage:

Apply a thin layer of the cream to the affected area(s) of the skin 2-3 times daily, or as directed by a healthcare provider. Wash hands before and after application. Do not cover the treated area with bandages or dressings unless directed to do so.

Side Effects:

Common side effects may include skin irritation, burning, itching, or redness at the application site. Severe allergic reactions are rare but seek medical attention if you experience a rash, swelling, or difficulty breathing.

Drug Interactions:

Inform your healthcare provider about all medications, supplements, and herbal products you are taking, as they may interact with the components of this medication. Drug interactions can affect the effectiveness or increase the risk of side effects.

Patient Counseling:

Patients should follow the prescribed dosage and application instructions provided by their healthcare provider. Avoid contact with eyes, mouth, or mucous membranes. If the condition worsens or does not improve, consult a healthcare professional. Keep out of reach of children.

Clinical Evidence:

Clinical studies have shown the efficacy of the combination of Ketoconazole, Neomycin Sulphate, Iodochlorhydroxyquinoline, Tolnaftate, and Clobetasol Propionate in treating various skin infections and inflammatory conditions. Consult your healthcare provider for more information on the clinical evidence supporting this medication.

Frequently Asked Questions:

1. Can this medication be used on children?
Children should use this medication under the supervision of a healthcare provider.

2. How long should I use this cream?
Use the medication for the duration prescribed by your healthcare provider, even if symptoms improve.

3. Can I apply cosmetics over the treated area?
Avoid applying cosmetics or other products over the treated skin unless advised by a healthcare provider.

4. What should I do if I miss a dose?
If you miss a dose, apply it as soon as you remember. However, if it’s almost time for the next dose, skip the missed dose and continue with your regular schedule.

Conclusion:

Ketoconazole + Neomycin Sulphate + Iodochlorhydroxyquinoline + Tolnaftate + Clobetasol Propionate cream is a versatile medication that combines multiple active ingredients to effectively treat a range of skin conditions. It is essential to follow the prescribed dosage, application instructions, and consult a healthcare provider for personalized advice regarding its use. This medication offers a comprehensive approach to managing skin infections, inflammation, and associated symptoms.

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