Name & Description:
The medicine is called GLIMEPIRIDE 3 MG + METFORMIN HYDROCHLORIDE 1000 MG (PR).
Active Ingredients:
The active ingredients in this medication are glimepiride and metformin hydrochloride.
Pharmacological Properties:
Glimepiride belongs to the sulfonylurea class of drugs, which work by increasing the release of insulin from the pancreas. Metformin, on the other hand, belongs to the biguanide class and works by decreasing glucose production in the liver and improving insulin sensitivity in the body.
Indications:
This medication is indicated for the treatment of type 2 diabetes mellitus in adults.
Contraindications:
This medication is contraindicated in patients with a history of hypersensitivity to sulfonylureas or metformin, severe kidney disease, or metabolic acidosis.
Dosage:
The usual starting dose is one tablet of glimepiride 3 mg + metformin hydrochloride 1000 mg once daily with meals. Dosage may be adjusted based on individual response and blood glucose levels.
Side Effects:
Common side effects of this medication may include hypoglycemia, nausea, vomiting, diarrhea, and abdominal discomfort. Contact your healthcare provider if any side effects persist or worsen.
Drug Interactions:
Glimepiride + metformin may interact with other medications such as certain antibiotics, antifungals, or diuretics. It is important to inform your healthcare provider about all the medications you are taking to avoid potential drug interactions.
Patient Counseling:
Patients should be advised to monitor their blood glucose levels regularly while taking this medication. It is important to follow a healthy diet and exercise regimen as recommended by your healthcare provider. In case of any unusual symptoms or side effects, seek medical attention promptly.
Clinical Evidence:
Clinical studies have demonstrated the efficacy of glimepiride + metformin combination therapy in improving glycemic control and reducing HbA1c levels in patients with type 2 diabetes.
Frequently Asked Questions (FAQs):
1. Can this medication be taken with food?
Yes, it is recommended to take this medication with meals to reduce the risk of gastrointestinal side effects.
2. What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
3. How long does it take for this medication to show effect?
Individual response to the medication may vary, but it is important to continue taking the medication as prescribed by your healthcare provider to achieve the desired therapeutic effect.
4. Are there any specific monitoring parameters while taking this medication?
Regular monitoring of blood glucose levels, kidney function tests, and liver function tests may be recommended by your healthcare provider to ensure safe and effective use of this medication.
5. Can this medication cause weight gain?
Weight gain is not a common side effect of this medication. However, lifestyle modifications such as a healthy diet and regular exercise are important in managing body weight.
