GLIMEPIRIDE 1 MG + PIOGLITAZONE 15 MG + METFORMIN HYDROCHLORIDE 500 MG SR
Description: The medicine contains a combination of Glimepiride, Pioglitazone, and Metformin Hydrochloride in specified dosages. It is manufactured by Bajaj Formulations and belongs to the Uncategorised category. Each strip contains 10 tablets with an actual MRP of Rs. 84, available at a discounted price of 25, which is a discount of 70.24%.
Active Ingredients:
The active ingredients in this medicine are Glimepiride, Pioglitazone, and Metformin Hydrochloride. Glimepiride is a sulfonylurea that helps lower blood sugar levels by stimulating the release of insulin from the pancreas. Pioglitazone is a thiazolidinedione that improves insulin sensitivity in the body. Metformin Hydrochloride is a biguanide that decreases glucose production in the liver and improves insulin sensitivity.
Pharmacological Properties:
This combination medicine works by addressing different aspects of diabetes management. Glimepiride and Pioglitazone help lower blood sugar levels through different mechanisms, while Metformin helps reduce liver glucose production and increases insulin sensitivity. The three medications together provide comprehensive control over blood sugar levels in patients with type 2 diabetes.
Indications:
This medicine is indicated for the treatment of type 2 diabetes mellitus in adults. It is used to improve blood sugar control in individuals who are not achieving adequate glycemic control with diet and exercise alone.
Contraindications:
This medicine is contraindicated in patients with a known hypersensitivity to any of the ingredients in the formulation. It should not be used in individuals with type 1 diabetes, diabetic ketoacidosis, severe renal impairment, or liver disease.
Dosage:
The prescribed dosage of Glimepiride 1 MG + Pioglitazone 15 MG + Metformin Hydrochloride 500 MG SR may vary depending on the patient’s individual needs and medical condition. It is important to follow the dosage instructions provided by the healthcare provider.
Side Effects:
Common side effects of this medicine may include hypoglycemia, gastrointestinal disturbances, weight gain, edema, and headache. It is essential to consult a healthcare professional if any adverse effects are experienced while taking this medication.
Drug Interactions:
This combination medicine may interact with certain other medications such as insulin, sulfonamides, and certain antihypertensive drugs. It is important to inform the healthcare provider about all the medications being taken to avoid potential drug interactions.
Patient Counseling:
- Patients should take the medication as prescribed by their healthcare provider.
- Regular monitoring of blood sugar levels is essential while on this medication.
- Avoid skipping doses and follow a healthy diet and exercise regimen as advised.
- Contact a healthcare professional in case of any unusual symptoms or side effects.
Clinical Evidence:
Several clinical studies have demonstrated the efficacy and safety of the combination of Glimepiride, Pioglitazone, and Metformin in the management of type 2 diabetes. These studies have shown improvements in glycemic control and overall metabolic parameters in patients using this combination therapy.
Frequently Asked Questions (FAQs):
1. What is the role of Glimepiride in this combination therapy?
Glimepiride helps to lower blood sugar levels by stimulating the release of insulin from the pancreas, thereby aiding in glycemic control.
2. How does Pioglitazone contribute to the effectiveness of this medicine?
Pioglitazone improves insulin sensitivity in the body, allowing for better utilization of insulin and improved blood sugar regulation.
3. What benefits does Metformin Hydrochloride offer in this medication?
Metformin Hydrochloride reduces glucose production in the liver and enhances insulin sensitivity, helping to control blood sugar levels in individuals with type 2 diabetes.
4. Are there any specific dietary recommendations to follow while taking this medicine?
It is advisable to follow a healthy diet low in simple sugars and carbohydrates while taking this medication to optimize its effectiveness in managing blood sugar levels.
5. Can the dosage of this medicine be adjusted based on individual response?
Yes, the dosage of Glimepiride 1 MG + Pioglitazone 15 MG + Metformin Hydrochloride 500 MG SR may be adjusted by the healthcare provider based on the patient’s response to the treatment and monitoring of blood sugar levels.
6. What should I do if I miss a dose of this medication?
If you miss a dose of this medication, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not double the dose to make up for a missed one.
7. Are there any long-term risks associated with the use of this combination therapy?
Long-term use of Glimepiride, Pioglitazone, and Metformin under the guidance of a healthcare provider is generally safe and effective for managing type 2 diabetes. Regular monitoring and follow-up are essential to assess the ongoing benefits and potential risks.
By providing comprehensive information on Glimepiride, Pioglitazone, and Metformin Hydrochloride combination therapy, patients can make informed decisions about their diabetes management in consultation with healthcare providers.
