GLICLAZIDE(SR) 30 MG + METFORMIN HYDROCHLORIDE(SR) 500 MG – Detailed Information

GLICLAZIDE(SR) 30 MG + METFORMIN HYDROCHLORIDE(SR) 500 MG is a combination medication that contains gliclazide and metformin hydrochloride. Gliclazide is a sulfonylurea antidiabetic medicine, while metformin is a biguanide antidiabetic medicine. This combination is commonly used to manage high blood sugar levels in patients with type 2 diabetes.

Active Ingredients

– Gliclazide 30 mg
– Metformin Hydrochloride 500 mg

Pharmacological Properties

– Gliclazide works by stimulating the release of insulin from the pancreas, which helps lower blood sugar levels.
– Metformin improves insulin sensitivity and reduces glucose production in the liver.

Indications

This medication is indicated for the treatment of type 2 diabetes in adults when diet and exercise alone are not sufficient to control blood sugar levels.

Contraindications

– Allergy to sulfonylureas or biguanides
– Severe kidney or liver disease
– Diabetic ketoacidosis
– Type 1 diabetes

Dosage

The typical starting dose is one tablet once or twice daily with meals. The dosage may be adjusted by a healthcare provider based on the individual’s response.

Side Effects

Common side effects may include:
– Hypoglycemia (low blood sugar)
– Nausea
– Diarrhea
– Abdominal discomfort

Drug Interactions

– Certain medications may interact with GLICLAZIDE(SR) 30 MG + METFORMIN HYDROCHLORIDE(SR) 500 MG, including:
– NSAIDs
– Beta-blockers
– ACE inhibitors
– Alcohol

Patient Counseling

Patients should be advised to:
– Take the medication with meals to reduce the risk of gastrointestinal side effects.
– Monitor blood sugar levels regularly as directed by their healthcare provider.
– Be aware of the signs and symptoms of hypoglycemia.

Clinical Evidence

Numerous clinical studies have demonstrated the efficacy of the combination of gliclazide and metformin in managing blood sugar levels in patients with type 2 diabetes. These studies have shown a reduction in HbA1c levels and improved glycemic control.

Frequently Asked Questions (FAQs)

1. What should I do if I miss a dose of GLICLAZIDE(SR) 30 MG + METFORMIN HYDROCHLORIDE(SR) 500 MG?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

2. Can I drink alcohol while taking this medication?

It is advisable to limit alcohol consumption while taking GLICLAZIDE(SR) 30 MG + METFORMIN HYDROCHLORIDE(SR) 500 MG, as alcohol can affect blood sugar levels and increase the risk of side effects.

3. How long does it take for this medication to start working?

The onset of action may vary among individuals, but some people may start to see improvements in blood sugar levels within a few days to weeks of starting the medication.

4. What precautions should I take while using this medication?

It is important to follow a healthy diet and exercise regimen as recommended by your healthcare provider while taking this medication. Monitor your blood sugar levels regularly and report any unusual symptoms to your doctor.

5. Can I drive or operate heavy machinery while taking GLICLAZIDE(SR) 30 MG + METFORMIN HYDROCHLORIDE(SR) 500 MG?

This medication may cause dizziness or drowsiness in some individuals. If you experience these side effects, avoid driving or operating heavy machinery until you know how the medication affects you.

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