GLICLAZIDE 60 MG + METFORMIN 500 MG (ER)
GLICLAZIDE 60 mg + METFORMIN 500 mg (Extended Release) is a combination medication used to treat type 2 diabetes. It contains two active ingredients, gliclazide and metformin, which work together to help control blood sugar levels in patients with diabetes.
Active Ingredients
This medication contains two active ingredients:
- Gliclazide 60 mg: It is a sulfonylurea medication that helps stimulate the release of insulin from the pancreas, which in turn helps lower blood sugar levels.
- Metformin 500 mg (Extended Release): Metformin is a biguanide medication that works by decreasing the production of glucose in the liver and improving the body’s response to insulin.
Pharmacological Properties
The combination of gliclazide and metformin in this medication provides complementary effects that help control blood sugar levels in patients with type 2 diabetes. Gliclazide stimulates insulin release, while metformin reduces glucose production and improves insulin sensitivity.
Indications
This medication is indicated for the treatment of type 2 diabetes in adults. It helps control blood sugar levels and reduce the risk of complications associated with diabetes when used as part of a comprehensive treatment plan that includes diet and exercise.
Contraindications
GLICLAZIDE 60 mg + METFORMIN 500 mg should not be used in the following circumstances:
- Patients with type 1 diabetes
- Patients with diabetic ketoacidosis
- Patients with severe kidney or liver disease
- Patients with a known hypersensitivity to sulfonylureas or biguanides
Dosage
The recommended dosage of GLICLAZIDE 60 mg + METFORMIN 500 mg is determined by a healthcare provider based on individual factors such as the patient’s blood sugar levels, overall health, and response to treatment. It is typically taken orally with meals to help reduce gastrointestinal side effects.
Side Effects
Common side effects of GLICLAZIDE 60 mg + METFORMIN 500 mg may include:
- Nausea
- Diarrhea
- Stomach upset
- Headache
- Hypoglycemia (low blood sugar)
It is important to report any severe or persistent side effects to a healthcare provider.
Drug Interactions
This medication may interact with other drugs, including:
- Diuretics
- Certain antibiotics
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Oral contraceptives
Patients should inform their healthcare provider about all medications, supplements, and herbal products they are taking to avoid potential interactions.
Patient Counseling
Patients taking GLICLAZIDE 60 mg + METFORMIN 500 mg should be counseled on the following:
- Proper administration of the medication
- Symptoms of hypoglycemia and how to manage low blood sugar levels
- The importance of regular monitoring of blood sugar levels
- Diet and exercise recommendations for managing diabetes
Clinical Evidence
Studies have shown that the combination of gliclazide and metformin is an effective treatment option for patients with type 2 diabetes. Clinical trials have demonstrated the benefits of using these two medications together to improve blood sugar control and reduce the risk of diabetes-related complications.
Frequently Asked Questions
1. How do gliclazide and metformin work together in this medication?
Gliclazide stimulates insulin release from the pancreas, while metformin reduces glucose production in the liver and improves the body’s response to insulin. Together, they help control blood sugar levels in patients with type 2 diabetes.
2. What are the common side effects of GLICLAZIDE 60 mg + METFORMIN 500 mg?
Common side effects may include nausea, diarrhea, stomach upset, headache, and hypoglycemia. Patients should report any severe or persistent side effects to their healthcare provider.
3. Who should not take this medication?
This medication is contraindicated in patients with type 1 diabetes, diabetic ketoacidosis, severe kidney or liver disease, or a known hypersensitivity to sulfonylureas or biguanides.
4. What should patients do in case of a missed dose?
If a dose of GLICLAZIDE 60 mg + METFORMIN 500 mg is missed, patients should take it as soon as they remember. However, if it is almost time for the next dose, they should skip the missed dose and continue with their regular dosing schedule. Patients should not double the dose to make up for a missed one.
5. Can this medication be used during pregnancy or breastfeeding?
Pregnant or breastfeeding women should consult their healthcare provider before taking this medication. The risks and benefits of using GLICLAZIDE 60 mg + METFORMIN 500 mg during pregnancy or breastfeeding should be discussed with a healthcare provider.
6. Are there any dietary restrictions while taking this medication?
Patients taking this medication should follow a healthy diet recommended by their healthcare provider to help manage blood sugar levels. It is important to avoid excessive alcohol consumption and maintain a balanced diet to support diabetes management.
7. How often should blood sugar levels be monitored while taking GLICLAZIDE 60 mg + METFORMIN 500 mg?
Patient blood sugar levels should be monitored regularly as directed by their healthcare provider to ensure the medication is effectively controlling blood sugar levels. Monitoring may involve self-testing at home or laboratory tests during healthcare visits.
8. What should I do if I experience severe hypoglycemia while taking this medication?
If a patient experiences severe hypoglycemia (low blood sugar) while taking GLICLAZIDE 60 mg + METFORMIN 500 mg, they should immediately consume a fast-acting source of glucose, such as fruit juice or candy, and seek medical attention if symptoms do not improve.
9. Can GLICLAZIDE 60 mg + METFORMIN 500 mg cause weight gain?
Weight gain is not a common side effect of this medication. In fact, some patients may experience weight loss due to improved blood sugar control and lifestyle modifications. Patients should consult their healthcare provider if they have concerns about weight changes while taking this medication.
10. What should I do if I accidentally take more than the prescribed dose of this medication?
If a patient accidentally takes more than the prescribed dose of GLICLAZIDE 60 mg + METFORMIN 500 mg, they should seek medical attention immediately. Overdosing on this medication can lead to serious complications, and prompt medical intervention is necessary to ensure proper treatment.
