GLICLAZIDE 40 MG + METFORMIN HYDROCHLORIDE 500 MG: A Comprehensive Overview
GLICLAZIDE 40 MG + METFORMIN HYDROCHLORIDE 500 MG is a medication produced by LIFE MAX CANCER. It falls under the category of Uncategorised medicines and is packaged in strips containing 10 tablets. The actual MRP of this medication is Rs. 67, but it is available at a discounted price of Rs. 24, amounting to a discount of 64.18%.
Active Ingredients
GLICLAZIDE and METFORMIN HYDROCHLORIDE are the active ingredients present in this medication. Each tablet contains 40 mg of GLICLAZIDE and 500 mg of METFORMIN HYDROCHLORIDE.
Pharmacological Properties
The combination of GLICLAZIDE and METFORMIN works synergistically to manage blood sugar levels in patients with diabetes. GLICLAZIDE belongs to the sulfonylurea class of drugs and acts by stimulating the release of insulin from the pancreas. On the other hand, METFORMIN is a biguanide that improves insulin sensitivity and reduces glucose production in the liver.
Indications
GLICLAZIDE 40 MG + METFORMIN HYDROCHLORIDE 500 MG is indicated for the treatment of type 2 diabetes mellitus in adults. It is prescribed to control blood sugar levels and prevent complications associated with diabetes.
Contraindications
This medication is contraindicated in patients with a history of hypersensitivity to sulfonylureas, metformin, or any other component of the formulation. It should not be used in individuals with severe kidney or liver dysfunction, ketoacidosis, or diabetic coma.
Dosage
The recommended dosage of GLICLAZIDE 40 MG + METFORMIN HYDROCHLORIDE 500 MG is one tablet twice daily with meals. The dose may vary depending on the patient’s response and blood glucose levels. It is important to follow the instructions of a healthcare provider when using this medication.
Side Effects
Common side effects of GLICLAZIDE and METFORMIN combination therapy include gastrointestinal symptoms such as nausea, vomiting, diarrhea, and abdominal discomfort. Hypoglycemia (low blood sugar) and lactic acidosis are rare but serious adverse effects that may occur with this medication.
Drug Interactions
GLICLAZIDE 40 MG + METFORMIN HYDROCHLORIDE 500 MG may interact with other medications, including certain antibiotics, antifungals, diuretics, and beta-blockers. It is essential to inform your healthcare provider about all the drugs you are taking to avoid potential interactions.
Patient Counseling
Patients should be counseled on the proper use of GLICLAZIDE and METFORMIN combination therapy, including adherence to the prescribed dosage, monitoring blood sugar levels regularly, and recognizing the signs of hypoglycemia. Lifestyle modifications such as a healthy diet and regular exercise are also important for managing diabetes effectively.
Clinical Evidence
Several clinical studies have demonstrated the effectiveness of GLICLAZIDE and METFORMIN in improving glycemic control and reducing the risk of diabetic complications. These medications are recommended as first-line therapy for type 2 diabetes due to their proven efficacy and safety profile.
Frequently Asked Questions (FAQs)
Q: Can GLICLAZIDE 40 MG + METFORMIN HYDROCHLORIDE 500 MG be used in patients with liver disease?
A: Individuals with severe liver dysfunction should avoid this medication due to the risk of lactic acidosis. It is essential to consult a healthcare provider before starting treatment.
Q: Is it safe to take GLICLAZIDE and METFORMIN together?
A: Yes, these medications are often prescribed in combination to achieve better blood sugar control in patients with type 2 diabetes. However, the dosage and potential side effects should be closely monitored.
Q: How quickly can I expect to see the effects of GLICLAZIDE 40 MG + METFORMIN HYDROCHLORIDE 500 MG?
A: The onset of action of this medication may vary among individuals. It is important to monitor your blood glucose levels regularly and follow up with your healthcare provider to assess the response to treatment.
Q: Are there any dietary restrictions while taking GLICLAZIDE and METFORMIN?
A: It is recommended to follow a healthy diet rich in fruits, vegetables, whole grains, and lean proteins while taking this medication. Avoiding excessive sugar intake and alcohol consumption can help in managing diabetes effectively.
Q: What should I do if I miss a dose of GLICLAZIDE 40 MG + METFORMIN HYDROCHLORIDE 500 MG?
A: If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.
Q: Can GLICLAZIDE 40 MG + METFORMIN HYDROCHLORIDE 500 MG cause weight gain?
A: Both GLICLAZIDE and METFORMIN are not known to cause significant weight gain. In fact, METFORMIN is associated with weight loss in some individuals due to its effects on insulin sensitivity and glucose metabolism.
