GLIBENCLAMIDE 5 MG
Glibenclamide 5 mg is a medication manufactured by SKYMAP PHARMA. It falls under the category of antidiabetic drugs but is commonly labeled as Uncategorised. Each strip contains 10 tablets, with an actual MRP of Rs. 14.65. However, it is available at a discounted price of Rs. 6, offering a discount of 59.04%.
Active Ingredients
Glibenclamide, also known as glyburide, is the active ingredient in this medication. It belongs to the sulfonylurea class of antidiabetic drugs.
Pharmacological Properties
Glibenclamide works by stimulating the release of insulin from the pancreas, helping to lower blood sugar levels. It also improves the sensitivity of body tissues to insulin, aiding in better glucose utilization.
Indications
Glibenclamide 5 mg is primarily indicated for the treatment of type 2 diabetes mellitus in adults. It is used alongside diet and exercise to control blood sugar levels.
Contraindications
This medication is contraindicated in patients with a history of hypersensitivity to sulfonylureas, diabetic ketoacidosis, type 1 diabetes, severe liver or kidney impairment, and during pregnancy and lactation.
Dosage
The usual recommended dose of glibenclamide is 5 mg once daily, preferably taken with breakfast or the first main meal of the day. Dosage adjustments should be made under medical supervision.
Side Effects
Common side effects of glibenclamide may include hypoglycemia, weight gain, gastrointestinal disturbances, skin reactions, and rare cases of liver toxicity. It is essential to report any adverse effects to your healthcare provider.
Drug Interactions
Glibenclamide may interact with certain medications such as NSAIDs, beta-blockers, corticosteroids, and some antibiotics, leading to altered blood sugar levels. Inform your doctor about all the medications you are taking before starting glibenclamide.
Patient Counseling
Patient counseling points for glibenclamide include the importance of regular blood sugar monitoring, adherence to diet and exercise routines, recognizing and managing hypoglycemic symptoms, and seeking medical help in case of any unusual side effects.
Clinical Evidence
Several clinical studies have demonstrated the efficacy and safety of glibenclamide in the management of type 2 diabetes. These trials have shown its ability to reduce hemoglobin A1c levels, improve insulin sensitivity, and lower the risk of diabetic complications when used appropriately.
Frequently Asked Questions (FAQs)
1. What is Glibenclamide used for?
Glibenclamide is primarily used for the treatment of type 2 diabetes mellitus in adults.
2. How should I take Glibenclamide?
The usual dose of glibenclamide is 5 mg once daily, taken with breakfast or the first main meal of the day. Follow your doctor’s instructions carefully.
3. What are the common side effects of Glibenclamide?
Common side effects may include hypoglycemia, weight gain, gastrointestinal issues, skin reactions, and rare cases of liver toxicity.
4. Can I take Glibenclamide during pregnancy?
Glibenclamide is not recommended during pregnancy. Consult your doctor for safer alternatives if you are pregnant or planning pregnancy.
5. Are there any food or drug interactions with Glibenclamide?
Glibenclamide may interact with certain medications and alcohol. Avoid alcohol consumption and inform your healthcare provider about all the medications you are taking.
These detailed insights into glibenclamide, its usage, effects, and precautions aim to enhance your understanding and encourage safe and effective use of this medication. Always consult your healthcare provider for personalized medical advice tailored to your specific needs.
