FILGRASTIM: Overview and Detailed Information

FILGRASTIM is a medication manufactured by DR. REDDY and falls under the category of Uncategorised medicines. It is available in injection form, with each vial containing one dose.

Active Ingredients

The active ingredient in FILGRASTIM is Filgrastim, which is a human granulocyte colony-stimulating factor (G-CSF) analog.

Pharmacological Properties

Filgrastim works by stimulating the bone marrow to produce more neutrophils, which are a type of white blood cell that helps the body fight off infections. It is commonly used to prevent or treat febrile neutropenia in patients undergoing chemotherapy.

Indications

FILGRASTIM is indicated for the following conditions:

  • Prevention of febrile neutropenia in patients undergoing chemotherapy

Contraindications

FILGRASTIM is contraindicated in patients with a history of hypersensitivity to Filgrastim or any of the components of the formulation.

Dosage

The dosage of FILGRASTIM may vary depending on the patient’s condition and the specific treatment regimen. It is important to follow the instructions provided by your healthcare provider or the medication label.

Side Effects

Common side effects of FILGRASTIM may include bone pain, fever, headache, nausea, and fatigue. In some cases, it may also cause allergic reactions or a very rare side effect called splenic rupture.

Drug Interactions

There are no known significant drug interactions with FILGRASTIM. However, it is important to inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medicines, and herbal supplements.

Patient Counseling

Patient counseling is essential for those receiving FILGRASTIM. Patients should be educated on the proper administration technique, potential side effects, and the importance of monitoring their white blood cell counts during treatment.

Clinical Evidence

Multiple clinical studies have demonstrated the efficacy of FILGRASTIM in reducing the incidence of febrile neutropenia and its associated complications in patients undergoing chemotherapy. Consult your healthcare provider for more information on the clinical evidence supporting the use of FILGRASTIM.

FAQ: Frequently Asked Questions

Q: What is the difference between Filgrastim and other colony-stimulating factors?

A: Filgrastim is a recombinant human granulocyte colony-stimulating factor that specifically stimulates the production of neutrophils. It is distinct from other colony-stimulating factors that target different types of blood cells.

Q: How should FILGRASTIM be stored?

A: FILGRASTIM should be stored in the refrigerator between 2°C to 8°C but should not be frozen. Do not shake the vial vigorously. Consult the medication label for specific storage instructions.

Q: Can FILGRASTIM be self-administered at home?

A: In some cases, FILGRASTIM may be administered at home under the supervision of a healthcare provider. Proper training and instruction are necessary for safe and effective self-administration.

Q: Is FILGRASTIM safe for use during pregnancy?

A: The safety of FILGRASTIM during pregnancy has not been established. Consult your healthcare provider before using this medication if you are pregnant or planning to become pregnant.

Q: What should I do if I miss a dose of FILGRASTIM?

A: If you miss a dose of FILGRASTIM, contact your healthcare provider for guidance. Do not double the dose to make up for a missed dose.

With its active ingredient Filgrastim, pharmacological properties, indications, contraindications, dosage, side effects, drug interactions, patient counseling, clinical evidence, and frequently asked questions, FILGRASTIM serves as an important medication in the management of febrile neutropenia in patients undergoing chemotherapy.

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