FENOFIBRATE 200 MG

Fenofibrate is a medication that belongs to the class of fibrates and is commonly prescribed for the management of high cholesterol and triglyceride levels in the blood. It works by decreasing the production of triglycerides and increasing the levels of good cholesterol (HDL) in the body. This helps reduce the risk of developing cardiovascular diseases such as heart attacks and strokes.

Active Ingredients

The active ingredient in Fenofibrate 200 mg is fenofibrate itself. Fenofibrate works by activating peroxisome proliferator-activated receptors (PPARs) in the liver and other tissues, which helps regulate lipid metabolism and reduce the levels of triglycerides and bad cholesterol (LDL) in the blood.

Pharmacological Properties

Fenofibrate exerts its pharmacological effects by decreasing triglyceride production in the liver, increasing the elimination of triglycerides, and promoting the uptake of cholesterol by liver cells. It also helps in improving insulin sensitivity and reducing inflammation in blood vessels.

Indications

Fenofibrate 200 mg is indicated for the treatment of:

– High levels of triglycerides (hypertriglyceridemia)
– Low levels of good cholesterol (HDL)
– Mixed dyslipidemia (abnormal levels of cholesterol and triglycerides)

Contraindications

Fenofibrate is contraindicated in patients with:

– Severe liver disease
– Gallbladder disease
– Allergy to fenofibrate or any component of the medication

Dosage

The usual recommended dose of Fenofibrate 200 mg is one tablet daily, with or without food. It is important to follow the dosage instructions provided by your healthcare provider to achieve the best results.

Side Effects

Common side effects of Fenofibrate may include:

– Upset stomach
– Diarrhea
– Headache
– Muscle pain
– Increased liver enzymes

If you experience any severe side effects such as severe abdominal pain, yellowing of the skin or eyes, or signs of an allergic reaction, seek medical attention immediately.

Drug Interactions

Fenofibrate may interact with certain medications, such as:

– Warfarin
– Statins (cholesterol-lowering medications)
– Cyclosporine

It is important to inform your healthcare provider about all the medications you are currently taking to avoid potential drug interactions.

Patient Counseling

Patients taking Fenofibrate should be counseled on:

– The importance of adhering to the prescribed dosage and schedule
– Dietary and lifestyle modifications to improve cholesterol levels
– Monitoring for potential side effects and reporting them to a healthcare provider

Clinical Evidence

Numerous clinical studies have demonstrated the efficacy of Fenofibrate in lowering triglyceride levels, increasing HDL cholesterol, and reducing the risk of cardiovascular events in patients with dyslipidemia. Consult your healthcare provider for more information on the clinical evidence supporting the use of Fenofibrate.

Frequently Asked Questions (FAQs)

Q: How long does it take for Fenofibrate to start working?

A: Fenofibrate may start showing its lipid-lowering effects within a few weeks of starting the medication. However, full therapeutic effects may take several weeks to months.

Q: Can I take Fenofibrate with other cholesterol medications?

A: It is essential to consult your healthcare provider before taking Fenofibrate with other cholesterol-lowering medications to avoid potential drug interactions.

Q: Is Fenofibrate safe for pregnant women?

A: Fenofibrate should not be used during pregnancy unless the potential benefits outweigh the risks. Consult your healthcare provider for guidance if you are pregnant or planning to become pregnant.

These FAQ answers provide additional information on Fenofibrate that may be helpful for patients considering or currently using this medication.

By providing comprehensive information on Fenofibrate, including its active ingredients, pharmacological properties, indications, contraindications, dosage, side effects, drug interactions, patient counseling, and clinical evidence, patients can make informed decisions regarding the use of this medication for their health needs.

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