DILTIAZEM HYDROCHLORIDE 60 MG
Diltiazem hydrochloride is a medication commonly prescribed to treat various cardiovascular conditions. It belongs to a class of drugs known as calcium channel blockers, which work by relaxing blood vessels and increasing the supply of blood and oxygen to the heart. The active ingredient in diltiazem hydrochloride is diltiazem.
Pharmacological Properties
Diltiazem hydrochloride exerts its pharmacological effects by inhibiting the influx of calcium ions into smooth muscle cells and myocardial cells. This action results in vasodilation of the coronary and peripheral arteries, reducing cardiac workload and oxygen demand. It also affects the electrical conduction within the heart, slowing down the heart rate and controlling abnormal heart rhythms.
Indications
Diltiazem hydrochloride is used to manage various cardiovascular conditions, including:
– Hypertension (high blood pressure)
– Angina pectoris (chest pain)
– Supraventricular tachycardia
– Atrial fibrillation or atrial flutter
Contraindications
Diltiazem hydrochloride should not be used in patients with:
– Hypersensitivity to diltiazem or any components of the formulation
– Severe hypotension (low blood pressure)
– Sick sinus syndrome
– Second- or third-degree atrioventricular block
Dosage
The dosage of diltiazem hydrochloride varies depending on the patient’s condition and response to the medication. It is typically taken orally in the form of tablets or capsules. The usual starting dose for hypertension is 120 to 240 mg per day, divided into two to four doses.
Side Effects
Common side effects of diltiazem hydrochloride may include:
– Dizziness
– Flushing
– Headache
– Fatigue
– Nausea or vomiting
– Constipation
Severe side effects that require immediate medical attention may include:
– Chest pain or tightness
– Shortness of breath
– Swelling of the hands, ankles, or feet
– Irregular heartbeat
Drug Interactions
Diltiazem hydrochloride may interact with other medications, including:
– Beta-blockers
– Digoxin
– Statins
– Cimetidine
– Rifampin
It is essential to inform your healthcare provider about all the medications you are taking to avoid potential drug interactions.
Patient Counseling
Patients taking diltiazem hydrochloride should be counseled on the following:
– Take the medication exactly as prescribed by your healthcare provider.
– Do not stop taking diltiazem suddenly without medical advice.
– Monitor your blood pressure regularly.
– Report any new or worsening symptoms to your healthcare provider.
Clinical Evidence
Clinical studies have demonstrated the efficacy of diltiazem hydrochloride in managing hypertension, angina, and certain cardiac arrhythmias. These studies have shown that diltiazem hydrochloride is effective in reducing blood pressure, improving exercise tolerance in angina patients, and controlling heart rate in arrhythmia patients.
Frequently Asked Questions (FAQs)
Q: Can diltiazem hydrochloride be taken with food?
A: Diltiazem hydrochloride can be taken with or without food, but it is essential to maintain a consistent intake pattern.
Q: How long does it take for diltiazem hydrochloride to start working?
A: Diltiazem hydrochloride may start working within a few hours, but it may take several weeks to see the full benefits of the medication.
Q: Can diltiazem hydrochloride be crushed or chewed?
A: Diltiazem hydrochloride should not be crushed or chewed, as it may alter the drug’s controlled-release properties.
Q: What should I do if I miss a dose of diltiazem hydrochloride?
A: If you miss a dose of diltiazem hydrochloride, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Q: Is it safe to drink alcohol while taking diltiazem hydrochloride?
A: It is best to avoid or limit alcohol consumption while taking diltiazem hydrochloride, as alcohol may increase the risk of side effects such as dizziness and drowsiness.
Conclusion
In conclusion, diltiazem hydrochloride is a commonly prescribed medication for various cardiovascular conditions. Understanding its active ingredients, pharmacological properties, indications, contraindications, dosage, side effects, drug interactions, and patient counseling is essential for safe and effective use. It is crucial to follow your healthcare provider’s instructions and monitor your health while taking diltiazem hydrochloride to achieve optimal results. If you have any concerns or questions about this medication, consult your healthcare provider for personalized advice and guidance.
