DILTIAZEM HYDROCHLORIDE 30 MG: Detailed Information
Diltiazem hydrochloride is a medication primarily used to treat high blood pressure and certain types of chest pain. It belongs to a class of drugs known as calcium channel blockers. This medication works by relaxing blood vessels and decreasing the heart’s workload, thereby improving blood flow and reducing strain on the heart.
Active Ingredients:
The active ingredient in this medication is diltiazem hydrochloride.
Pharmacological Properties:
Diltiazem hydrochloride exerts its pharmacological effects by inhibiting the influx of calcium ions into cardiac and smooth muscle cells. This action results in vasodilation, decreased peripheral resistance, and reduced myocardial contractility.
Indications:
Diltiazem hydrochloride is indicated for the treatment of:
– Hypertension (high blood pressure)
– Chronic stable angina
– Variant angina
– Supraventricular tachycardia
Contraindications:
This medication is contraindicated in patients with:
– Hypersensitivity to diltiazem or other components of the formulation
– Severe hypotension
– Sick sinus syndrome
– Second- or third-degree atrioventricular block
Dosage:
The usual starting dose of diltiazem hydrochloride for hypertension is 30 mg orally three to four times daily. The dosage may be adjusted based on individual response.
Side Effects:
Common side effects of diltiazem hydrochloride may include:
– Dizziness
– Headache
– Flushing
– Nausea
– Fatigue
Rare but serious side effects may include:
– Bradycardia
– Hypotension
– Liver dysfunction
– Allergic reactions
Drug Interactions:
Diltiazem hydrochloride may interact with other medications such as:
– Beta-blockers
– Digoxin
– Statins
– Cimetidine
– Rifampicin
It is essential to inform your healthcare provider about all the medications you are taking to avoid potential drug interactions.
Patient Counseling:
Patients taking diltiazem hydrochloride should be counseled on the following points:
– Take the medication exactly as prescribed by your healthcare provider.
– Avoid consuming grapefruit or grapefruit juice while on this medication as it may increase diltiazem levels in the blood.
– Report any unusual symptoms or side effects to your healthcare provider promptly.
Clinical Evidence:
Clinical studies have demonstrated the efficacy of diltiazem hydrochloride in the management of hypertension and angina. This medication has been shown to effectively reduce blood pressure and improve exercise tolerance in patients with angina pectoris.
Frequently Asked Questions (FAQs):
Q: Can I take diltiazem hydrochloride with food?
A: This medication can be taken with or without food. However, it is essential to maintain a consistent diet to ensure proper drug absorption.
Q: How long does it take for diltiazem hydrochloride to start working?
A: The onset of action of diltiazem hydrochloride varies but may start to work within 1 to 2 hours after administration.
Q: Is diltiazem hydrochloride safe for use during pregnancy?
A: It is important to consult your healthcare provider before using diltiazem hydrochloride during pregnancy as it may pose risks to the fetus.
Q: Can I suddenly stop taking diltiazem hydrochloride?
A: It is not recommended to abruptly discontinue diltiazem hydrochloride without consulting your healthcare provider as it may lead to adverse effects.
By providing comprehensive information on diltiazem hydrochloride, including its active ingredients, pharmacological properties, indications, contraindications, dosage, side effects, drug interactions, patient counseling, clinical evidence, and frequently asked questions, patients can make informed decisions about this medication. Remember to always consult with your healthcare provider before starting or stopping any medication.
