DARUNAVIR
Darunavir is a medication manufactured by Cipla and belongs to the Uncategorised category of medicines. It is available in a strip packing type containing 60 tablets. The actual MRP of Darunavir is Rs. 9757.44, but it is being offered at a discounted price of Rs. 6409, providing a discount of 34.32%.
Active Ingredients
Darunavir contains the active ingredient Darunavir ethanolate, which is a type of protease inhibitor used in the treatment of HIV infections.
Pharmacological Properties
Darunavir works by blocking the activity of the protease enzyme, which is necessary for the HIV virus to replicate and spread in the body. This inhibition helps to control the viral load and prevent the progression of HIV infection to AIDS.
Indications
Darunavir is indicated for the treatment of HIV-1 infection in adult and pediatric patients. It is usually used in combination with other antiretroviral medications as part of a comprehensive treatment regimen for HIV.
Contraindications
Darunavir is contraindicated in individuals with known hypersensitivity to any of the components of the medication. It should not be used in patients with severe hepatic impairment.
Dosage
The recommended dosage of Darunavir for adults is typically 800 mg once daily with ritonavir 100 mg to boost its levels in the body. The exact dosage and frequency may vary based on individual patient factors, so it is important to follow the prescription provided by a healthcare professional.
Side Effects
Common side effects of Darunavir may include nausea, diarrhea, headache, rash, and elevated liver enzymes. Patients may also experience metabolic abnormalities and changes in fat distribution with long-term use.
Drug Interactions
Darunavir can interact with a variety of medications, including other antiretrovirals, certain antibiotics, antifungals, and medications metabolized by the CYP3A4 enzyme system. Patients should inform their healthcare provider about all medications they are taking to prevent potential interactions.
Patient Counseling
Patients taking Darunavir should be advised to take the medication exactly as prescribed, without missing doses. It is important to attend regular follow-up appointments to monitor the response to treatment and any potential side effects. Patients should also be educated on the importance of adherence to the full course of antiretroviral therapy.
Clinical Evidence
Clinical studies have demonstrated the efficacy of Darunavir in significantly reducing viral load and improving CD4 cell counts in HIV-infected patients. It has been shown to be effective in both treatment-naive and treatment-experienced individuals when used in combination with other antiretroviral agents.
Frequently Asked Questions
1. Can Darunavir cure HIV completely?
No, Darunavir is not a cure for HIV. It is used to control the viral replication and progression of the infection but does not eliminate the virus from the body. Treatment with Darunavir and other antiretroviral medications aims to manage HIV as a chronic condition.
2. What should I do if I miss a dose of Darunavir?
If you miss a dose of Darunavir, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.
3. Are there any dietary restrictions while taking Darunavir?
There are no specific dietary restrictions associated with Darunavir. However, it is important to maintain a healthy and balanced diet to support overall health and immune function while undergoing HIV treatment.
4. How long do I need to take Darunavir?
The duration of Darunavir treatment will be determined by your healthcare provider based on your individual condition and response to therapy. It is essential to continue taking the medication as prescribed, even if you feel better, to prevent the development of drug resistance.
5. Can pregnant women take Darunavir?
Pregnant women should consult with their healthcare provider before taking Darunavir, as the medication may be prescribed in specific cases where the benefits outweigh the potential risks to the fetus. Close monitoring and coordination with a healthcare team are essential for pregnant women with HIV.
This expanded content provides detailed information about Darunavir, including its active ingredients, pharmacological properties, indications, contraindications, dosage, side effects, drug interactions, patient counseling, and clinical evidence. The FAQ section addresses common questions related to the medication, offering comprehensive guidance to users.
