DAPAGLIFLOZIN + METFORMIN HYDROCHLORIDE: A Comprehensive Guide
Dapagliflozin 5 mg + Metformin Hydrochloride 500 mg (SR) is a combination medication used in the treatment of type 2 diabetes. This medication is manufactured by Stafford Laboratories and belongs to the category of Uncategorised medicines. The medicine is packaged in strips of 10 tablets. The actual MRP of this medicine is Rs. 148, while the discounted price is Rs. 69, providing a discount of 53.38%.
Active Ingredients
Dapagliflozin and Metformin Hydrochloride are the active ingredients present in this medication. Dapagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor that works by helping the kidneys remove glucose from the bloodstream through the urine. Metformin Hydrochloride belongs to the biguanide class of drugs and helps decrease the amount of glucose produced by the liver.
Pharmacological Properties
Dapagliflozin + Metformin Hydrochloride combination works synergistically to control blood sugar levels in patients with type 2 diabetes. Dapagliflozin inhibits glucose reabsorption in the kidneys, causing excess glucose to be excreted in the urine. Metformin lowers blood sugar levels by reducing glucose production in the liver and improving insulin sensitivity in the body.
Indications
This combination medication is indicated for the management of type 2 diabetes in adults. It is typically prescribed alongside diet and exercise to improve glycemic control in patients who require both Dapagliflozin and Metformin as part of their treatment regimen.
Contraindications
– Allergy to Dapagliflozin, Metformin, or any other ingredients in the medication
– Severe renal impairment
– Metabolic acidosis
– Type 1 diabetes
– Diabetic ketoacidosis
– Severe dehydration
Dosage
The dosage of Dapagliflozin 5 mg + Metformin Hydrochloride 500 mg (SR) should be individualized based on the patient’s condition and response to treatment. It is important to follow the dosage instructions provided by your healthcare provider. Typically, the medication is taken orally with a meal to minimize gastrointestinal side effects.
Side Effects
Common side effects of Dapagliflozin + Metformin Hydrochloride may include:
– Nausea
– Diarrhea
– Headache
– Urinary tract infection
– Hypoglycemia when used with insulin or sulfonylureas
It is essential to report any severe or persistent side effects to your healthcare provider.
Drug Interactions
Dapagliflozin + Metformin Hydrochloride may interact with other medications, including:
– Diuretics
– ACE Inhibitors
– Insulin
– Corticosteroids
– Phenytoin
Inform your healthcare provider about all the medications you are currently taking to avoid potential drug interactions.
Patient Counseling
Before starting Dapagliflozin + Metformin Hydrochloride therapy, patients should be counseled on:
– Proper medication use and dosing schedule
– Potential side effects and when to seek medical help
– Importance of regular monitoring of blood sugar levels
– Lifestyle modifications such as diet and exercise to improve diabetes management
Clinical Evidence
Clinical studies have shown that the combination of Dapagliflozin and Metformin Hydrochloride is effective in lowering blood sugar levels and improving glycemic control in patients with type 2 diabetes. These medications have been found to be well-tolerated and have a favorable safety profile when used as prescribed.
Frequently Asked Questions (FAQ)
1. Can Dapagliflozin + Metformin Hydrochloride be used to treat type 1 diabetes?
No, this medication is specifically indicated for the management of type 2 diabetes and should not be used in patients with type 1 diabetes.
2. What should I do if I miss a dose of Dapagliflozin + Metformin Hydrochloride?
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed dose.
3. How long does it take for Dapagliflozin + Metformin Hydrochloride to start working?
The onset of action of these medications may vary from person to person. It is essential to follow your healthcare provider’s recommendations and monitor your blood sugar levels regularly to assess the effectiveness of the treatment.
4. Are there any dietary restrictions while taking Dapagliflozin + Metformin Hydrochloride?
While there are no specific dietary restrictions, it is advisable to follow a healthy diet low in sugar and carbohydrates to help manage blood sugar levels effectively. Consult with a healthcare provider or a dietitian for personalized dietary recommendations.
5. Can I drink alcohol while taking Dapagliflozin + Metformin Hydrochloride?
It is generally safe to consume alcohol in moderation while taking this medication. However, alcohol consumption can affect blood sugar levels, so it is important to monitor your blood sugar closely and be aware of any potential interactions between alcohol and Dapagliflozin + Metformin Hydrochloride.
This comprehensive guide provides detailed information about Dapagliflozin + Metformin Hydrochloride, including its active ingredients, pharmacological properties, indications, contraindications, dosage, side effects, drug interactions, patient counseling, and clinical evidence. For more personalized information, consult your healthcare provider or pharmacist.
