DAPAGLIFLOZIN 10 MG + METFORMIN HYDROCHLORIDE 500 MG (SR)
Dapagliflozin 10 mg + Metformin Hydrochloride 500 mg is a combination medication used in the management of type 2 diabetes. It combines two different classes of antidiabetic drugs that work together to help control blood sugar levels in patients with diabetes.
Active Ingredients
The active ingredients in Dapagliflozin 10 mg + Metformin Hydrochloride 500 mg are dapagliflozin and metformin hydrochloride. Dapagliflozin belongs to the class of drugs known as sodium-glucose cotransporter 2 (SGLT2) inhibitors, while metformin hydrochloride is a biguanide antidiabetic medication.
Pharmacological Properties
Dapagliflozin works by inhibiting the SGLT2 transporter in the kidneys, which reduces reabsorption of glucose and increases the excretion of glucose in the urine. Metformin primarily reduces glucose production in the liver and improves insulin sensitivity in the body.
Indications
Dapagliflozin 10 mg + Metformin Hydrochloride 500 mg is indicated for the treatment of type 2 diabetes mellitus in adults to improve glycemic control.
Contraindications
This medication is contraindicated in patients with a history of hypersensitivity to dapagliflozin, metformin, or any other components of the formulation. It should be used with caution in patients with renal impairment, hepatic impairment, or certain medical conditions.
Dosage
The usual recommended dose of Dapagliflozin 10 mg + Metformin Hydrochloride 500 mg is one tablet taken orally once or twice daily, as directed by a healthcare provider. The dosage may vary based on individual patient needs and response to treatment.
Side Effects
Common side effects of this medication may include urinary tract infections, genital yeast infections, increased urination, thirst, dizziness, gastrointestinal disturbances, and hypoglycemia. It is important to report any unusual or severe side effects to a healthcare professional.
Drug Interactions
Dapagliflozin 10 mg + Metformin Hydrochloride 500 mg may interact with other medications, including diuretics, glucocorticoids, and certain antidiabetic agents. Patients should inform their healthcare provider about all the medications they are taking to avoid potential interactions.
Patient Counseling
Patients taking Dapagliflozin 10 mg + Metformin Hydrochloride 500 mg should be educated about the importance of adhering to the prescribed dosage regimen, monitoring blood sugar levels regularly, maintaining a healthy diet, staying hydrated, and seeking medical advice if they experience any concerning symptoms.
Clinical Evidence
Several clinical studies have demonstrated the efficacy and safety of dapagliflozin and metformin in managing type 2 diabetes. These studies have shown improvements in glycemic control, weight management, and cardiovascular outcomes in patients treated with this combination therapy.
Frequently Asked Questions (FAQs)
1. How should I take Dapagliflozin 10 mg + Metformin Hydrochloride 500 mg?
It is recommended to take this medication exactly as prescribed by your healthcare provider. Do not alter the dosage or frequency without consulting a doctor.
2. What should I do if I miss a dose of Dapagliflozin 10 mg + Metformin Hydrochloride 500 mg?
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
3. Are there any dietary restrictions while taking Dapagliflozin 10 mg + Metformin Hydrochloride 500 mg?
It is important to follow a healthy diet recommended by your healthcare provider while taking this medication. Avoid excessive consumption of alcohol and high-carbohydrate foods that may affect blood sugar control.
4. Can I drive or operate machinery while on Dapagliflozin 10 mg + Metformin Hydrochloride 500 mg?
Some patients may experience dizziness or drowsiness as side effects of this medication. If you experience these symptoms, avoid driving or operating heavy machinery until you are sure of how the medication affects you.
5. How long does it take for Dapagliflozin 10 mg + Metformin Hydrochloride 500 mg to show results?
The time to see the full effects of this medication may vary from individual to individual. It is important to continue taking the medication as prescribed and monitor your blood sugar levels regularly as advised by your healthcare provider.
6. What should I do in case of an overdose of Dapagliflozin 10 mg + Metformin Hydrochloride 500 mg?
If you suspect an overdose or experience severe symptoms such as severe hypoglycemia, seek immediate medical attention or contact a poison control center for assistance.
For more information on Dapagliflozin 10 mg + Metformin Hydrochloride 500 mg, consult your healthcare provider or pharmacist.
