DANAZOL 100 MG
Danazol 100 mg is a medication produced by Clevus Lifesciences. It falls under the category of medicines that are Uncategorised. Each pack of Danazol 100 mg contains 10 tablets. The actual Maximum Retail Price (MRP) of the medicine is Rs. 239, but it is currently available at a discounted price of Rs. 170, which reflects a discount of 28.87%.
Active Ingredients
Danazol is the active ingredient in Danazol 100 mg tablets. It is a synthetic steroid derived from ethisterone and has both androgenic and anabolic properties.
Pharmacological Properties
Danazol acts by suppressing the pituitary-ovarian axis, leading to a decrease in estrogen production and an increase in androgen levels. It also has weak progestational activity.
Indications
Danazol 100 mg is indicated for the treatment of endometriosis, fibrocystic breast disease, and hereditary angioedema. It is also sometimes used in the management of menorrhagia and premenstrual syndrome (PMS).
Contraindications
Danazol should not be used in patients with a history of hepatic dysfunction, porphyria, undiagnosed vaginal bleeding, or hypersensitivity to the drug. It is contraindicated in pregnancy and should not be used by breastfeeding mothers.
Dosage
The usual dose of Danazol 100 mg is determined based on the condition being treated. It is typically taken orally with food to reduce gastrointestinal upset. The dosage may vary from patient to patient, so it is essential to follow the instructions provided by a healthcare provider.
Side Effects
Common side effects of Danazol 100 mg include weight gain, acne, oily skin, menstrual irregularities, and hot flushes. Rare but serious side effects may include liver dysfunction, jaundice, and signs of masculinization in females.
Drug Interactions
Danazol may interact with certain medications, including anticoagulants, insulin, cyclosporine, and tacrolimus. It is essential to inform the healthcare provider about all medications, including prescription, over-the-counter, and herbal supplements, before starting Danazol therapy.
Patient Counseling
Patients taking Danazol should be advised to attend regular follow-up visits with their healthcare providers to monitor for efficacy and side effects. They should also be educated about the need for contraception during Danazol therapy, as it can cause harm to a developing fetus.
Clinical Evidence
Several clinical studies have demonstrated the efficacy of Danazol in the treatment of endometriosis and hereditary angioedema. It has been shown to reduce symptoms such as pelvic pain, menstrual irregularities, and swelling attacks in patients with these conditions.
Frequently Asked Questions (FAQs)
Q: How long does it take for Danazol to start working?
A: The onset of action of Danazol may vary from person to person and depending on the condition being treated. Some patients may experience symptom improvement within a few weeks, while others may require several months of therapy for full benefit.
Q: Can Danazol be used in male patients?
A: Danazol is not typically recommended for use in male patients due to its androgenic properties, which can lead to virilization and other unwanted effects. It is primarily used in females for the conditions mentioned earlier.
Q: Is it safe to take Danazol during pregnancy?
A: No, Danazol is contraindicated in pregnancy due to the potential harm it can cause to the developing fetus. It is essential to use effective contraception while taking Danazol and to discontinue the medication if pregnancy occurs.
Q: What should I do if I miss a dose of Danazol?
A: If you miss a dose of Danazol, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.
Q: Can Danazol interact with herbal supplements?
A: Yes, Danazol may interact with certain herbal supplements, especially those with hormonal effects or potential liver toxicity. It is crucial to inform your healthcare provider about all supplements you are taking to avoid potential drug interactions.
In conclusion, Danazol 100 mg is a medication used in various gynecological and endocrine conditions and hereditary angioedema. It is essential to take Danazol as directed by a healthcare provider and to be aware of its potential side effects and interactions. If you have any further questions or concerns about Danazol, consult with your healthcare provider for personalized advice.
