Introduction to Cinacalcet 30 mg
Cinacalcet 30 mg is a medication produced by Clevus Lifesciences, belonging to the Uncategorised category. Each pack contains 10 tablets. The original Maximum Retail Price (MRP) for Cinacalcet 30 mg is Rs. 653; however, it is currently being offered at a discounted price of Rs. 250, providing a discount of 61.72%.
Active Ingredients
The active ingredient in Cinacalcet 30 mg is cinacalcet hydrochloride. Cinacalcet works by increasing the sensitivity of the parathyroid gland to calcium levels in the blood, leading to a decrease in parathyroid hormone levels.
Pharmacological Properties
Cinacalcet is classified as a calcimimetic agent. It acts by binding to and activating calcium-sensing receptors on the parathyroid gland, resulting in decreased parathyroid hormone secretion. This mechanism helps in regulating calcium levels in the blood.
Indications
Cinacalcet is prescribed for the treatment of hyperparathyroidism in patients with chronic kidney disease on dialysis, primary hyperparathyroidism, and parathyroid carcinoma. It is also used in the management of hypercalcemia in patients with parathyroid cancer.
Contraindications
Cinacalcet is contraindicated in patients with a known hypersensitivity to cinacalcet or any of the ingredients in the formulation. It is also not recommended for use in patients with severe hypocalcemia or impaired gastrointestinal motility.
Dosage
The usual recommended starting dose of Cinacalcet 30 mg is 30 mg once daily. The dose may be titrated based on the patient’s response and serum calcium levels. It is important to follow the dosage instructions provided by the healthcare provider.
Side Effects
Common side effects of Cinacalcet may include nausea, vomiting, diarrhea, dizziness, and hypocalcemia. Serious side effects such as seizures, severe uncontrolled vomiting, and allergic reactions are rare but may occur. It is crucial to report any unusual symptoms to a healthcare professional.
Drug Interactions
Cinacalcet may interact with other medications such as strong CYP2D6 inhibitors, ketoconazole, and rifampin. These interactions can affect the efficacy or safety of Cinacalcet. It is essential to inform the healthcare provider about all the medications being taken to avoid potential drug interactions.
Patient Counseling
Patients prescribed Cinacalcet should be educated on the importance of regular monitoring of calcium levels and adherence to the prescribed dosage regimen. They should also be informed about possible side effects and when to seek medical help.
Clinical Evidence
Multiple clinical studies have demonstrated the efficacy of Cinacalcet in managing hyperparathyroidism and hypercalcemia. The drug has shown significant reductions in parathyroid hormone levels and improved calcium balance in patients with these conditions.
Frequently Asked Questions (FAQs)
1. Can I take Cinacalcet with food?
Cinacalcet can be taken with or without food. However, it is advisable to follow the specific instructions provided by your healthcare provider.
2. How long does it take for Cinacalcet to start working?
The onset of action of Cinacalcet may vary among individuals. It is essential to follow the prescribed dosage regimen and attend follow-up appointments for monitoring.
3. What should I do if I miss a dose of Cinacalcet?
If you miss a dose of Cinacalcet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
4. Are there any special precautions to be taken while using Cinacalcet?
Patients taking Cinacalcet should be cautious about driving or operating machinery, especially if they experience dizziness or weakness as side effects. It is advisable to avoid consuming alcohol while on Cinacalcet therapy.
5. Can Cinacalcet be used during pregnancy or breastfeeding?
The use of Cinacalcet during pregnancy or breastfeeding should be determined by a healthcare provider after evaluating the potential risks and benefits. It is important to discuss any pregnancy plans or breastfeeding intentions with a healthcare professional.
By providing comprehensive information on Cinacalcet, including its active ingredients, pharmacological properties, indications, contraindications, dosage, side effects, drug interactions, patient counseling, clinical evidence, and frequently asked questions, individuals can make informed decisions about the medication. It is crucial to consult a healthcare provider before initiating Cinacalcet therapy to ensure safe and effective treatment.
