CHLORTHALIDONE 12.5 MG: Overview
Chlorthalidone 12.5 mg is a medication manufactured by Tulbros Formulations. It belongs to the category of medicine that is Uncategorised. The medicine is available in a strip packing type containing 10 tablets.
Active Ingredients:
Chlorthalidone is the active ingredient present in each tablet of 12.5 mg chlorthalidone. It is a diuretic that works by increasing the excretion of water and sodium by the kidneys.
Pharmacological Properties:
Chlorthalidone is a thiazide diuretic that acts by inhibiting the reabsorption of sodium and chloride ions in the distal convoluted tubule of the kidney, leading to increased excretion of sodium and water. This results in a decrease in extracellular fluid volume and reduction in blood pressure.
Indications:
Chlorthalidone 12.5 mg is indicated for the treatment of hypertension (high blood pressure) and edema (fluid retention) associated with conditions such as congestive heart failure, liver cirrhosis, and kidney disorders.
Contraindications:
Chlorthalidone should not be used in patients with an allergy to chlorthalidone or other sulfonamide-derived medications. It is contraindicated in patients with severe renal impairment, hepatic coma, or electrolyte imbalances such as hypokalemia (low potassium levels).
Dosage:
The usual dosage of chlorthalidone 12.5 mg for hypertension is one tablet taken orally once daily. The dosage may be adjusted based on individual response to treatment and should be taken consistently at the same time each day.
Side Effects:
Common side effects of chlorthalidone may include dizziness, lightheadedness, weakness, electrolyte imbalances (such as low potassium), increased uric acid levels, and photosensitivity. Rare but serious side effects may include severe skin reactions, renal impairment, and hypotension.
Drug Interactions:
Chlorthalidone may interact with other medications such as nonsteroidal anti-inflammatory drugs (NSAIDs), lithium, digoxin, and certain antidiabetic drugs. It is important to inform your healthcare provider about all the medications you are taking to avoid potential drug interactions.
Patient Counseling:
Patients taking chlorthalidone should be advised to follow a low-sodium diet, stay hydrated, and monitor their blood pressure regularly. It is important to report any side effects or symptoms of electrolyte imbalances to their healthcare provider promptly.
Clinical Evidence:
Several clinical studies have demonstrated the efficacy of chlorthalidone in lowering blood pressure and reducing edema. Chlorthalidone has been shown to be effective in reducing the risk of cardiovascular events in patients with hypertension.
Frequently Asked Questions (FAQs):
1. Is chlorthalidone a diuretic?
Yes, chlorthalidone is a thiazide diuretic that helps the kidneys eliminate excess water and salt from the body.
2. How long does it take for chlorthalidone to start working?
Chlorthalidone may start lowering blood pressure within a few hours, but it may take a few weeks to reach its full effect.
3. Can chlorthalidone cause potassium loss?
Yes, chlorthalidone can cause potassium loss, so your healthcare provider may monitor your potassium levels regularly.
4. What should I do if I miss a dose of chlorthalidone?
If you miss a dose of chlorthalidone, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
5. Can I take chlorthalidone with other blood pressure medications?
It is possible to take chlorthalidone with other blood pressure medications, but you should only do so under the guidance of your healthcare provider to avoid potential drug interactions.
6. Is chlorthalidone safe during pregnancy and breastfeeding?
Chlorthalidone is not recommended during pregnancy and breastfeeding as it may harm the developing fetus or pass into breast milk.
By providing comprehensive information on chlorthalidone, patients can make informed decisions about its use and better manage their health conditions. It is essential to consult with a healthcare professional for personalized advice and treatment recommendations.
