Benidipine hydrochloride is a medication used in the management of hypertension. It belongs to the class of calcium channel blockers and works by relaxing the blood vessels, allowing the heart to pump more easily. This helps lower blood pressure and improve blood flow.

Active Ingredients:

The active ingredient in Benidipine hydrochloride is benidipine hydrochloride itself.

Pharmacological Properties:

Benidipine hydrochloride acts as a calcium channel blocker, specifically targeting L-type calcium channels in the blood vessels. By blocking these channels, it inhibits the influx of calcium ions, leading to vasodilation and reduced peripheral vascular resistance. This results in decreased blood pressure and improved blood flow to vital organs.


Benidipine hydrochloride is indicated for the treatment of hypertension (high blood pressure). It may be used alone or in combination with other antihypertensive agents.


Benidipine hydrochloride is contraindicated in patients with a known hypersensitivity to the drug or any of its components. It should also be avoided in patients with severe hypotension, heart failure, or a history of angioedema related to previous calcium channel blocker therapy.


The usual recommended dose of Benidipine hydrochloride is 4 mg once daily. Dosage may be adjusted based on individual patient response and tolerability. It is important to follow the prescribing healthcare provider’s instructions regarding dosage and administration.

Side Effects:

Common side effects of Benidipine hydrochloride may include dizziness, headache, edema, flushing, and palpitations. In some cases, it may also cause hypotension, gastrointestinal disturbances, and skin reactions. Patients should report any unusual or persistent side effects to their healthcare provider.

Drug Interactions:

Benidipine hydrochloride may interact with other medications, such as beta-blockers, ACE inhibitors, and diuretics, potentially altering their effects. Patients should inform their healthcare provider about all the medications they are taking, including prescription, over-the-counter, and herbal supplements.

Patient Counseling:

Patients taking Benidipine hydrochloride should be advised to follow a healthy lifestyle, including a balanced diet, regular exercise, and stress management. They should also be informed about the potential side effects and drug interactions associated with the medication. Regular monitoring of blood pressure and clinical parameters may be recommended.

Clinical Evidence:

Several clinical studies have demonstrated the efficacy and safety of Benidipine hydrochloride in the management of hypertension. These studies have shown significant reductions in blood pressure levels with minimal adverse effects. However, individual responses to the medication may vary, and close monitoring is essential during treatment.

Frequently Asked Questions:

1. How long does it take for Benidipine hydrochloride to start working?

Benidipine hydrochloride may start lowering blood pressure within a few hours of the first dose, but noticeable effects may take several weeks of consistent use.

2. Can I take Benidipine hydrochloride with food?

Benidipine hydrochloride can be taken with or without food. However, it is advisable to maintain a consistent routine regarding food intake to ensure the medication’s effectiveness.

3. What should I do if I miss a dose of Benidipine hydrochloride?

If you miss a dose of Benidipine hydrochloride, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

4. Is Benidipine hydrochloride safe for use in elderly patients?

Benidipine hydrochloride can be used in elderly patients with caution, as they may be more sensitive to its effects. A lower starting dose and gradual titration may be recommended to minimize the risk of adverse reactions.

5. Can I stop taking Benidipine hydrochloride if my blood pressure is under control?

It is important not to discontinue Benidipine hydrochloride without consulting your healthcare provider, even if your blood pressure is well-controlled. Abruptly stopping the medication can lead to rebound hypertension or other adverse effects.

6. What should I do if I experience severe side effects while taking Benidipine hydrochloride?

If you experience severe or life-threatening side effects while taking Benidipine hydrochloride, seek immediate medical attention and discontinue the medication until further evaluation by a healthcare provider.

7. Is it safe to drive or operate machinery while taking Benidipine hydrochloride?

Benidipine hydrochloride may cause dizziness or drowsiness as side effects. Therefore, it is advisable to exercise caution while driving or operating machinery until you are aware of how the medication affects you.

8. Can I drink alcohol while taking Benidipine hydrochloride?

Alcohol consumption should be limited while taking Benidipine hydrochloride, as it can potentiate the medication’s effects on blood pressure and increase the risk of side effects. Consult your healthcare provider for personalized advice.

9. How should Benidipine hydrochloride tablets be stored?

Benidipine hydrochloride tablets should be stored at room temperature away from moisture and heat. Keep them out of reach of children and pets, and always check the expiration date before use.

10. Is there a generic version of Benidipine hydrochloride available?

Generic versions of Benidipine hydrochloride may be available under different brand names. Patients should consult their healthcare provider or pharmacist for information on generic alternatives and their suitability.

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