Azilsartan medoxomil is a medication used to treat high blood pressure. It belongs to a class of drugs known as angiotensin II receptor blockers (ARBs). This medication works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and reducing the workload on the heart.

Active Ingredients:

Azilsartan medoxomil is the active ingredient in this medication. Once inside the body, azilsartan medoxomil is converted to azilsartan, which is responsible for its pharmacological effects.

Pharmacological Properties:

Azilsartan medoxomil works by selectively blocking the angiotensin II receptor. By doing so, it helps to relax blood vessels, lower blood pressure, and improve blood flow. This medication does not affect other hormone systems involved in blood pressure regulation.


Azilsartan medoxomil is indicated for the treatment of hypertension (high blood pressure) in adults. It may be used alone or in combination with other antihypertensive medications as prescribed by a healthcare provider.


Azilsartan medoxomil should not be used in patients who are allergic to azilsartan or any other inactive ingredients in the formulation. It is also contraindicated in pregnant women, as it may cause harm to the unborn baby.


The usual recommended starting dose of azilsartan medoxomil is 40 mg once daily. The dosage may be adjusted by a healthcare provider based on individual response and tolerability. This medication can be taken with or without food.

Side Effects:

Common side effects of azilsartan medoxomil may include dizziness, headache, diarrhea, and fatigue. In rare cases, this medication may cause more serious side effects such as allergic reactions, kidney problems, or high potassium levels. Patients should seek medical attention if they experience any severe side effects.

Drug Interactions:

Azilsartan medoxomil may interact with other medications such as potassium-sparing diuretics, nonsteroidal anti-inflammatory drugs (NSAIDs), and lithium. It is important to inform healthcare providers of all medications being taken to prevent potential drug interactions.

Patient Counseling:

Patients should take azilsartan medoxomil exactly as prescribed by their healthcare provider. It is important to continue taking this medication even if feeling well, as high blood pressure often has no symptoms. Patients should also follow a healthy lifestyle with a balanced diet, regular exercise, and stress management to help control blood pressure.

Clinical Evidence:

Several clinical studies have demonstrated the efficacy of azilsartan medoxomil in lowering blood pressure and reducing the risk of cardiovascular events. Long-term use of this medication has been shown to be safe and well-tolerated in most patients.

Frequently Asked Questions:

1. Can I take azilsartan medoxomil if I am pregnant?

Azilsartan medoxomil is not recommended during pregnancy as it may cause harm to the unborn baby. If you are pregnant or planning to become pregnant, consult your healthcare provider for alternative treatment options.

2. How quickly will I see the effects of azilsartan medoxomil on my blood pressure?

Individual responses may vary, but most patients start to see a reduction in blood pressure within a few weeks of starting azilsartan medoxomil treatment. It is essential to continue taking the medication as directed for optimal results.

3. Are there any dietary restrictions when taking azilsartan medoxomil?

There are no specific dietary restrictions with azilsartan medoxomil. However, it is essential to follow a healthy diet low in salt, saturated fats, and cholesterol to help manage high blood pressure effectively.

4. Can I drink alcohol while taking azilsartan medoxomil?

Moderate alcohol consumption is generally acceptable while taking azilsartan medoxomil. However, excessive alcohol intake may affect blood pressure control and interact with the medication. It is best to consult with your healthcare provider for personalized advice.

5. What should I do if I miss a dose of azilsartan medoxomil?

If you miss a dose of azilsartan medoxomil, take it as soon as you remember. However, if it is close to the next scheduled dose, skip the missed dose and continue with the regular dosing schedule. Do not double up on doses to make up for a missed dose.

6. Can azilsartan medoxomil be taken with other blood pressure medications?

Azilsartan medoxomil can be used in combination with other antihypertensive medications as prescribed by a healthcare provider. It is important to follow the recommended dosing schedule and inform your doctor of all medications you are taking to avoid potential drug interactions.

7. Is azilsartan medoxomil safe for older adults?

Azilsartan medoxomil is generally safe for use in older adults. However, dosage adjustments may be necessary based on kidney function and overall health status. Healthcare providers should carefully monitor elderly patients taking this medication for any potential side effects or interactions.

8. What should I do if I experience side effects while taking azilsartan medoxomil?

If you experience any unusual or bothersome side effects while taking azilsartan medoxomil, contact your healthcare provider promptly. Do not stop the medication abruptly without medical advice, as sudden discontinuation may lead to rebound hypertension or other complications.

9. Can azilsartan medoxomil be used in patients with kidney disease?

Azilsartan medoxomil can be used in patients with kidney disease, but dosage adjustments may be necessary depending on the level of kidney function. It is essential to inform your healthcare provider about any kidney conditions to ensure safe and effective use of this medication.

10. Is azilsartan medoxomil covered by insurance plans?

Coverage for azilsartan medoxomil may vary depending on your insurance provider and individual plan. It is recommended to check with your insurance company or pharmacist to determine if this medication is covered and what out-of-pocket costs may apply.

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