ATORVASTATIN + ASPIRIN: Detailed Information
Medicine Name: Atorvastatin 20 mg + Aspirin 150 mg
Manufacturer: Unimarck Healthcare Ltd.
Category: Uncategorised
Packing Type: Strip of 15 Capsules
Actual MRP: Rs. 112.5
Discounted Price: Rs. 45
Discount: 60%
Active Ingredients
The combination of Atorvastatin and Aspirin contains the following active ingredients:
- Atorvastatin: It is a statin medication used to lower cholesterol levels in the blood by inhibiting an enzyme responsible for cholesterol production.
- Aspirin: Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) that helps reduce pain, inflammation, and prevent blood clots.
Pharmacological Properties
The pharmacological properties of Atorvastatin and Aspirin encompass their individual mechanisms of action:
- Atorvastatin: Works by blocking the enzyme HMG-CoA reductase, which plays a key role in cholesterol synthesis, leading to reduced cholesterol levels in the blood.
- Aspirin: Inhibits the enzyme cyclooxygenase (COX), thereby reducing the formation of prostaglandins, which are mediators of pain, inflammation, and clot formation.
Indications
Atorvastatin + Aspirin is indicated for the following conditions:
- Hypercholesterolemia (High cholesterol levels)
- Cardiovascular disease prevention
- Antiplatelet therapy to reduce the risk of clot formation
Contraindications
Do not use Atorvastatin + Aspirin if you have the following conditions:
- History of aspirin allergy or intolerance
- Active or recent gastrointestinal bleeding
- Severe liver or kidney disease
Dosage
The typical dosage of Atorvastatin 20 mg + Aspirin 150 mg is one capsule daily, or as directed by a healthcare professional.
Side Effects
Common side effects of Atorvastatin + Aspirin may include:
- Stomach upset
- Headache
- Muscle pain or weakness
Drug Interactions
Atorvastatin + Aspirin may interact with the following medications:
- Anticoagulants like Warfarin
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Certain antibiotics
Patient Counseling
Patient counseling points for Atorvastatin + Aspirin use:
- Follow the prescribed dosage and schedule
- Report any unusual side effects to your healthcare provider
- Avoid alcohol consumption while taking this medication
Clinical Evidence
Several clinical studies have demonstrated the efficacy of Atorvastatin + Aspirin in reducing cholesterol levels and preventing cardiovascular events.
Frequently Asked Questions (FAQs)
1. Can I take Atorvastatin + Aspirin if I have a history of stomach ulcers?
It is advisable to consult your healthcare provider before taking this medication if you have a history of stomach ulcers to assess the risk versus benefit.
2. How long does it take for Atorvastatin + Aspirin to show its effects on cholesterol levels?
The effects of Atorvastatin on cholesterol levels may be seen within a few weeks of starting the medication, whereas Aspirin’s antiplatelet effects are immediate.
3. What should I do if I miss a dose of Atorvastatin + Aspirin?
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
4. Is it safe to consume grapefruit while taking Atorvastatin + Aspirin?
Grapefruit and grapefruit juice may interact with Atorvastatin, potentially increasing the risk of side effects. Avoid grapefruit products unless advised otherwise by your healthcare provider.
