THALIDOMIDE 100 MG: A Comprehensive Guide
Medicine Description: Thalidomide 100 mg is a medication manufactured by Fresenies Kabi, falling under the category of Uncategorised medicines. It comes in a strip packaging containing 10 tablets. The actual MRP of the medicine is Rs. 779, but it is available at a discounted price of Rs. 440, providing a discount of 43.52%.
Active Ingredients:
Thalidomide contains the active ingredient Thalidomide, which is a synthetic derivative of glutamic acid.
Pharmacological Properties:
Thalidomide exerts its pharmacological effects primarily through its anti-inflammatory, immunomodulatory, and sedative properties. It is known to inhibit the synthesis of inflammatory cytokines and regulate the immune response.
Indications:
Thalidomide is indicated for the treatment of various conditions, including:
- Multiple myeloma
- Erythema nodosum leprosum
- Behcet’s disease
- Severe recurrent aphthous stomatitis
Contraindications:
Thalidomide is contraindicated in:
- Pregnant women
- Women of childbearing potential who are not using effective contraception
Dosage:
The recommended dosage of Thalidomide 100 mg should be determined by a healthcare professional based on the specific condition being treated. It is usually taken orally once daily.
Side Effects:
Common side effects of Thalidomide may include:
- Drowsiness
- Constipation
- Rash
- Fatigue
- Peripheral neuropathy
Drug Interactions:
Thalidomide may interact with certain medications, including:
- Warfarin
- Rifampicin
- Oral contraceptives
Patient Counseling:
Patients taking Thalidomide should be advised to:
- Avoid pregnancy during treatment and for a certain period after discontinuation
- Report any unusual symptoms or side effects to their healthcare provider
Clinical Evidence:
Several clinical studies have demonstrated the efficacy and safety of Thalidomide in the treatment of multiple myeloma and other conditions. Consult your healthcare provider for more information on the latest clinical evidence.
Frequently Asked Questions (FAQs):
Q: What is the mechanism of action of Thalidomide?
Thalidomide exerts its effects by modulating the activity of certain inflammatory cytokines and immune cells, leading to its anti-inflammatory and immunomodulatory properties.
Q: Can Thalidomide be used during pregnancy?
No, Thalidomide is absolutely contraindicated in pregnant women due to its well-known teratogenic effects, which can lead to severe birth defects.
Q: How should Thalidomide be stored?
Thalidomide should be stored at room temperature away from moisture and heat, preferably in a tightly closed container.
Q: What should I do if I miss a dose of Thalidomide?
If you miss a dose of Thalidomide, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
Q: Can Thalidomide cause drowsiness?
Yes, drowsiness is a common side effect of Thalidomide. It is advisable to avoid activities that require mental alertness, such as driving or operating machinery, until you know how this medication affects you.
Q: Are there any dietary restrictions while taking Thalidomide?
There are no specific dietary restrictions associated with Thalidomide. However, it is recommended to follow a healthy and balanced diet as advised by your healthcare provider.
Consult your healthcare provider or pharmacist for more information on Thalidomide, including its benefits, risks, and proper usage.
