PANTOPRAZOLE 40 + LEVOSULPIRIDE 75 MG SR: A Comprehensive Guide

When it comes to managing gastrointestinal disorders, Pantoprazole 40mg + Levosulpiride 75mg SR, manufactured by Bajaj Formulations, serves as a potent combination. This medication falls under the category of gastrointestinal medicines and is available in a convenient strip packing of 10 capsules. While the actual MRP of this medication is Rs. 200, customers can benefit from a discounted price of Rs. 86, representing a significant discount of 57%.

Active Ingredients

Pantoprazole, a proton pump inhibitor (PPI), is the primary active ingredient in this combination medication. It works by reducing the production of stomach acid, thereby alleviating symptoms of acid reflux and related conditions. Levosulpiride, on the other hand, is a prokinetic agent that enhances gastrointestinal motility, making it useful in treating conditions like gastroparesis.

Pharmacological Properties

Pantoprazole acts by irreversibly inhibiting the H+/K+ ATPase enzyme system in the gastric parietal cells, leading to a reduction in acid secretion. Levosulpiride exerts its prokinetic effects by enhancing the release of acetylcholine, which in turn stimulates gastric emptying and reduces symptoms of bloating and indigestion.

Indications

This medication is indicated for the management of various gastrointestinal conditions, including gastroesophageal reflux disease (GERD), peptic ulcers, dyspepsia, and functional dyspepsia. It is also beneficial in treating conditions characterized by delayed gastric emptying, such as diabetic gastroparesis.

Contraindications

Pantoprazole 40mg + Levosulpiride 75mg SR is contraindicated in individuals with a known hypersensitivity to any of the ingredients in the formulation. It should be used with caution in patients with severe hepatic impairment or certain electrolyte imbalances.

Dosage

The recommended dosage of Pantoprazole 40mg + Levosulpiride 75mg SR is one capsule to be taken orally once daily, preferably before a meal. The duration of treatment may vary depending on the underlying condition and the individual response to therapy. It is important to follow the prescribed regimen and not exceed the recommended dose.

Side Effects

Like all medications, Pantoprazole 40mg + Levosulpiride 75mg SR may cause side effects in some individuals. Common side effects include headache, nausea, abdominal discomfort, diarrhea, and fatigue. Serious adverse reactions such as allergic reactions or severe gastrointestinal disturbances are rare but should be reported to a healthcare provider immediately.

Drug Interactions

There are potential drug interactions to consider when taking Pantoprazole 40mg + Levosulpiride 75mg SR. It is important to inform your healthcare provider about all the medications, supplements, and herbal products you are taking to avoid interactions that could affect the efficacy or safety of this medication. In particular, this combination medication may interact with certain anticoagulants, antifungals, and antidepressants.

Patient Counseling

Patients should be counseled on the proper use of Pantoprazole 40mg + Levosulpiride 75mg SR, including the importance of taking it as prescribed and adhering to dietary and lifestyle modifications recommended by their healthcare provider. It is essential to report any unusual or persistent side effects to the healthcare team promptly.

Clinical Evidence

Numerous clinical studies have demonstrated the efficacy and safety of Pantoprazole and Levosulpiride in the management of gastrointestinal disorders. These studies have shown significant improvements in symptoms such as heartburn, regurgitation, and bloating, leading to a better quality of life for patients receiving this combination therapy.

Frequently Asked Questions (FAQs)

Q: How long does it take for Pantoprazole 40mg + Levosulpiride 75mg SR to start working?


A: The onset of action of this medication may vary, but some patients may experience symptom relief within a few days of starting treatment.

Q: Can Pantoprazole 40mg + Levosulpiride 75mg SR be taken with other medications?


A: It is essential to consult your healthcare provider before taking this medication with other drugs to avoid potential interactions that could affect its efficacy or safety.

Q: Are there any dietary restrictions to follow while taking Pantoprazole 40mg + Levosulpiride 75mg SR?


A: Patients may be advised to avoid certain foods or beverages that can exacerbate gastrointestinal symptoms, such as spicy foods, alcohol, and caffeine.

Q: What should I do if I miss a dose of Pantoprazole 40mg + Levosulpiride 75mg SR?


A: If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Q: Can Pantoprazole 40mg + Levosulpiride 75mg SR be taken during pregnancy or while breastfeeding?


A: It is important to consult your healthcare provider before using this medication during pregnancy or breastfeeding to assess the potential risks and benefits.

In conclusion, Pantoprazole 40mg + Levosulpiride 75mg SR is a valuable combination medication for the management of gastrointestinal disorders. By understanding its active ingredients, pharmacological properties, indications, and other essential information, patients can make informed decisions about its use under the guidance of healthcare professionals. If you have further questions or concerns about this medication, do not hesitate to consult your healthcare provider for personalized advice.

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