GLICLAZIDE 30 MG (SR) + PIOGLITAZONE HCL 15 MG + METFORMIN HCL 500 MG SR
Manufacturer: INNOVA CAP
Category: Uncategorised
Packing Type: Strip of 10 tablets
Actual MRP: Rs. 86
Discounted Price: Rs. 60
Discount: 30.23%
Active Ingredients
The medicine combines three active ingredients: Gliclazide 30 mg (SR), Pioglitazone HCL 15 mg, and Metformin HCL 500 mg SR.
Pharmacological Properties
Gliclazide is a sulfonylurea derivative that works by stimulating the release of insulin from pancreatic beta cells. Pioglitazone is a thiazolidinedione that enhances insulin sensitivity. Metformin is a biguanide that reduces glucose production in the liver and improves insulin sensitivity in peripheral tissues.
Indications
This medication is indicated for the treatment of type 2 diabetes mellitus in adults when diet and exercise alone are not sufficient to control blood glucose levels.
Contraindications
It is contraindicated in patients with known hypersensitivity to any of the components of the formulation, severe renal impairment, severe hepatic impairment, and type 1 diabetes mellitus.
Dosage
The usual dosage of this combination medication is one tablet taken orally once or twice daily with meals, as directed by a healthcare provider.
Side Effects
Common side effects may include hypoglycemia, weight gain, upper respiratory tract infections, edema, and gastrointestinal disturbances. Rare but serious side effects may include lactic acidosis and hepatotoxicity.
Drug Interactions
This medication may interact with other drugs such as rifampicin, cimetidine, and certain antifungal agents. It is important to consult a healthcare provider before starting or stopping any medications while on this combination therapy.
Patient Counseling
Patients should be educated about the importance of adherence to treatment, monitoring of blood glucose levels, signs and symptoms of hypoglycemia, and lifestyle modifications such as diet and exercise. Regular follow-up with a healthcare provider is crucial for optimal diabetes management.
Clinical Evidence
Several clinical studies have demonstrated the efficacy and safety of the combination of gliclazide, pioglitazone, and metformin in the management of type 2 diabetes mellitus. These studies have shown improvements in glycemic control and cardiovascular outcomes in patients treated with this medication.
Frequently Asked Questions
1. What are the key active ingredients in this medication?
The key active ingredients are gliclazide, pioglitazone, and metformin.
2. How should I take this medication?
Take this medication orally as directed by your healthcare provider, usually with meals once or twice daily.
3. What should I do in case I miss a dose?
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
4. What are the common side effects of this medication?
Common side effects may include hypoglycemia, weight gain, upper respiratory tract infections, edema, and gastrointestinal disturbances.
5. Are there any serious side effects I should be aware of?
Rare but serious side effects may include lactic acidosis and hepatotoxicity. If you experience any unusual symptoms, seek medical attention immediately.
6. Can I take other medications along with this combination therapy?
It is important to consult your healthcare provider before taking any other medications, as they may interact with this combination therapy.
7. How long does it take for this medication to show its effects?
The onset of action and full benefits of this medication may vary from individual to individual. It is important to regularly monitor your blood glucose levels and follow up with your healthcare provider for adjustments in treatment if needed.
Remember to always consult your healthcare provider for personalized medical advice and treatment recommendations.
