Introduction:


Isoniazid 300mg Tablet is a prescription medication manufactured by Cadila Pharmaceuticals Ltd. It contains the active ingredient Isoniazid in a dosage of 300mg per tablet. This medicine belongs to the therapeutic class of ANTI INFECTIVES and has a chemical class of Nicotinic acid derivatives. Isoniazid is classified as a Mycolic acid inhibitor and is commonly used in the treatment of Tuberculosis (TB).

Uses:


Isoniazid 300mg Tablet is primarily prescribed for the treatment of Tuberculosis (TB). It works by inhibiting the synthesis of mycolic acid in the cell wall of the tuberculosis bacteria, thereby preventing their growth and multiplication in the body.

Price:


The Maximum Retail Price (MRP) of Isoniazid 300mg Tablet is ₹1.75 for a strip of 10 tablets.

Dosage:


It is essential to take Isoniazid 300mg Tablet in the dose and duration prescribed by your doctor. The tablet should be swallowed whole and should not be chewed, crushed, or broken. It is recommended to take this medication on an empty stomach for optimal absorption.

Benefits:


The benefits of using Isoniazid 300mg Tablet include the effective treatment of Tuberculosis (TB) by targeting the bacteria responsible for the infection. Proper usage of this medication as directed by a healthcare professional can help in eradicating the bacteria and improving the patient’s condition.

Side Effects:


Some of the common side effects associated with Isoniazid 300mg Tablet may include:
– Peripheral neuropathy (tingling and numbness of feet and hand)
– Increased liver enzymes
– Hepatitis (viral infection of the liver)
– Jaundice

It is important to consult a doctor if any of these side effects persist or worsen over time.

Active Ingredients:


The active ingredient in Isoniazid 300mg Tablet is Isoniazid, which is a key component responsible for its anti-tubercular properties.

Pharmacological Properties:


Isoniazid exerts its pharmacological effects by inhibiting the synthesis of mycolic acid, a vital component of the bacterial cell wall in Mycobacterium tuberculosis. This action disrupts the integrity of the bacterial cell wall, leading to bacterial death and clearance from the body.

Indications:


Isoniazid 300mg Tablet is indicated for the treatment of Tuberculosis (TB) caused by susceptible strains of Mycobacterium tuberculosis. It is commonly used in combination with other anti-tubercular drugs as part of a comprehensive treatment regimen.

Contraindications:


Isoniazid 300mg Tablet should not be used in individuals with a known hypersensitivity or allergy to Isoniazid or any of its components. Additionally, it is contraindicated in patients with severe liver disease or a history of drug-induced hepatitis.

Drug Interactions:


There are potential drug interactions to be aware of when using Isoniazid 300mg Tablet. It is important to inform your healthcare provider about all the medications, supplements, and herbal products you are currently taking to avoid any potential interactions. Some common drug interactions may include interactions with rifampicin, phenytoin, and alcohol.

Patient Counseling:


Patients using Isoniazid 300mg Tablet should be counseled on the following points:
– Take the medication as prescribed by your healthcare provider
– Do not alter the dosage or frequency of administration without medical advice
– Report any unusual or persistent side effects to your doctor
– Follow a healthy diet and lifestyle while on treatment
– Avoid the consumption of tyramine-rich foods along with Isoniazid

Clinical Evidence:


Several clinical studies and trials have demonstrated the efficacy of Isoniazid in the treatment of Tuberculosis. The use of Isoniazid in combination with other anti-tubercular drugs has shown significant success rates in the management of TB infections.

Frequently Asked Questions:

1. Can Isoniazid 300mg Tablet be taken with food?


It is recommended to take Isoniazid 300mg Tablet on an empty stomach to optimize its absorption and effectiveness.

2. Is Isoniazid habit-forming?


No, Isoniazid is not known to be habit-forming and does not possess addictive properties.

3. What should I do if I miss a dose of Isoniazid 300mg Tablet?


If you miss a dose of Isoniazid, try to take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

4. Can I consume alcohol while taking Isoniazid 300mg Tablet?


It is advisable to avoid alcohol consumption while on treatment with Isoniazid, as it may increase the risk of liver damage and adverse effects.

5. How long does it take for Isoniazid to show results in TB treatment?


The time taken for Isoniazid to exhibit therapeutic effects in Tuberculosis treatment may vary depending on individual factors. It is essential to complete the full course of treatment as prescribed by your doctor for optimal outcomes.

6. Are there any specific monitoring requirements while on Isoniazid therapy?


Regular monitoring of liver function tests may be recommended by your healthcare provider while on Isoniazid therapy to assess for any potential liver-related side effects.

7. Can Isoniazid be used during pregnancy or breastfeeding?


It is important to consult with your doctor before using Isoniazid during pregnancy or while breastfeeding, as the potential risks and benefits need to be evaluated for each individual case.

8. What should I do if I experience any allergic reactions to Isoniazid?


If you suspect an allergic reaction to Isoniazid, such as rash, itching, or difficulty breathing, seek immediate medical attention and discontinue the medication.

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MRP:

₹1.75

Manufacturer:

Cadila Pharmaceuticals Ltd

Salt:

Isoniazid (300mg),

How to UseIsoniazid 300mg Tablet:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isoniazid 300mg Tablet is to be taken empty stomach.
Avoid Isoniazid 300mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

Side Effects of Isoniazid 300mg Tablet:

Peripheral neuropathy (tingling and numbness of feet and hand),Increased liver enzymes,Hepatitis (viral infection of liver),Jaundice,

Alternate Medicines for Isoniazid 300mg Tablet:

Lup Inh 300mg Tablet,Isonij 300mg Tablet,Solonex Tablet,Isonex 300mg Tablet,

Prescription Required Status:

Prescription Required

Type of Selection:

strip of 10 tablets

Chemical Class:

Nicotinic acid derivatives

Habit Forming:

No

Therapeutic Class:

ANTI INFECTIVES

Action Class:

Mycolic acid inhibitors- INH

. Please note, this information is for educational purposes only and not intended as medical advice.

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